Complications and mid-term outcome after percutaneous patent foramen ovale closure in patients with cryptogenic stroke

J. G.L.M. Luermans, M. C. Post, H. W.M. Plokker, J. M. Ten Berg, M. J. Suttorp

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18 Citations (Scopus)

Abstract

Background: Percutaneous patent foramen ovale (PFO) closure seems to reduce the risk of recurrent thromboembolism. We report the safety and efficacy of percutaneous PFO closure in our centre. Methods: All patients, >16 years of age, who underwent a percutaneous PFO closure in our centre were included. Reoccurrence of stroke, transient ischaemic attack (TIA) and peripheral thromboembolism were assessed. Periprocedural and midterm complications are reported. Results: Eighty-three consecutive patients (mean age 49±13 years) were included. Indications for PFO closure were cryptogenic stroke (59.0%), TIA (33.7%), peripheral embolism (2.4%) and other (4.8%). For PFO closure, a Cardioseal/Starflex device was used in 63 patients and an Amplatzer PFO occluder device in 20 patients. Stroke recurred in 1.2%, TIA in 3.6%, peripheral embolism in 0% during a mean follow-up of 1.9±1.2 years. Major periprocedural complications occurred in 1.2%. The mid-term complication rate was 2.4% and only consisted of minor complications. During follow-up, a residual right-to-left shunt was present in 5.7% of the patients. No significant difference in outcome, complications or residual shunting could be documented between the two device types. Conclusion: In our centre, the percutaneous closure of a PFO seems to be a safe and effective procedure to prevent recurrence of paradoxical thromboembolic events.

Original languageEnglish
Pages (from-to)332-336
Number of pages5
JournalNetherlands Heart Journal
Volume16
Issue number10
DOIs
Publication statusPublished - 1 Jan 2008

Keywords

  • Cryptogenic stroke
  • Patent foramen ovale
  • Percutaneous closure
  • Safety

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