Comparison of the incidences of cardiac arrhythmias, myocardial ischemia, and cardiac events in patients treated with endovascular versus open surgical repair of abdominal aortic aneurysms

Harm H H Feringa, Stefanos Karagiannis, Radosav Vidakovic, Peter G Noordzij, Jasper J Brugts, Olaf Schouten, Marc R H M van Sambeek, Jeroen J Bax, Don Poldermans*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

This study examines differences in cardiac arrhythmias, perioperative myocardial ischemia, troponin T release, and cardiovascular events between endovascular and open repair of abdominal aortic aneurysms (AAAs). Of 175 patients, 126 underwent open AAA repair and 49 underwent endovascular AAA repair. Continuous 12-lead electrocardiographic monitoring, starting 1 day before surgery and continuing through 2 days after surgery, was used for cardiac arrhythmia and myocardial ischemia detection. Troponin T was measured on postoperative days 1, 3, and 7 and before discharge. Cardiac events (cardiac death or Q-wave myocardial infarction) were noted at 30 days and at follow-up (mean 2.3 years). New-onset atrial fibrillation, nonsustained ventricular tachycardia, sustained ventricular tachycardia, and ventricular fibrillation occurred in 5%, 17%, 2%, and 1% of patients, respectively. Myocardial ischemia, troponin T release, and 30-day and long-term cardiac events occurred in 34%, 29%, 6%, and 10% of patients, respectively. Significantly higher heart rates and less heart rate variability were observed in the open AAA repair group. Cardiac arrhythmias were less prevalent in the endovascular AAA repair group (14% vs 29%, p = 0.04). Endovascular repair was also significantly associated with less myocardial ischemia (odds ratio 0.14, 95% confidence interval 0.05 to 0.40, p <0.001) and troponin T release (odds ratio 0.10, 95% confidence interval 0.02 to 0.32, p <0.001) and lower 30-day mortality (zero vs 8.7%, p = 0.03) and 30-day cardiac event rates (zero vs 7.9%, p = 0.04). Long-term mortality and cardiac event rates were not significantly lower in the endovascular AAA repair group. In conclusion, endovascular AAA repair is associated with a lower incidence of perioperative cardiac arrhythmias, myocardial ischemia, troponin T release, cardiac events, and all-cause mortality compared with open AAA repair.

Original languageEnglish
Pages (from-to)1479-1784
Number of pages6
JournalThe American Journal of Cardiology
Volume100
Issue number9
DOIs
Publication statusPublished - 1 Nov 2007
Externally publishedYes

Keywords

  • Aged
  • Aortic Aneurysm, Abdominal/surgery
  • Arrhythmias, Cardiac/epidemiology
  • Atrial Fibrillation/epidemiology
  • Blood Vessel Prosthesis Implantation
  • Echocardiography, Stress
  • Electrocardiography
  • Female
  • Heart Rate/physiology
  • Humans
  • Male
  • Multivariate Analysis
  • Myocardial Ischemia/epidemiology
  • Prospective Studies
  • Stents
  • Tachycardia, Ventricular/epidemiology
  • Treatment Outcome
  • Troponin T/blood
  • Vascular Surgical Procedures

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