Comparison of MBT biotargets with MBT steel targets for matrix-assisted laser desorption/ionization time of flight mass spectrometry identifications of microorganisms in a clinical microbiology laboratory

Robert K P Schouten; Valentijn A Schweitzer; Sebastian van Marm; Rob J Rentenaar

doi:10.1016/j.diagmicrobio.2024.116270

Comparison of MBT biotargets with MBT steel targets for matrix-assisted laser desorption/ionization time of flight mass spectrometry identifications of microorganisms in a clinical microbiology laboratory

Robert K P Schouten, Valentijn A Schweitzer, Sebastian van Marm, Rob J Rentenaar^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

MALDI-TOF MS identifications of microorganisms in a clinical laboratory were investigated, comparing steel targets with MBT Biotargets. By using MBT Biotargets, the score values of yeast identifications increased, whereas the score values of Gram-negative bacteria decreased. Switching to MBT Biotargets did not negatively impact overall frequencies of high confidence identifications.

Original language	English
Article number	116270
Journal	Diagnostic Microbiology and Infectious Disease
Volume	109
Issue number	2
DOIs	https://doi.org/10.1016/j.diagmicrobio.2024.116270
Publication status	Published - Jun 2024

Keywords

Biotarget
Identification
MALDI-TOF MS
Steel target
Yeast

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10.1016/j.diagmicrobio.2024.116270Licence: CC BY

1-s2.0-S0732889324000993-mainFinal published version, 1.18 MBLicence: CC BY

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Schouten, R. K. P., Schweitzer, V. A., van Marm, S., & Rentenaar, R. J. (2024). Comparison of MBT biotargets with MBT steel targets for matrix-assisted laser desorption/ionization time of flight mass spectrometry identifications of microorganisms in a clinical microbiology laboratory. Diagnostic Microbiology and Infectious Disease, 109(2), Article 116270. https://doi.org/10.1016/j.diagmicrobio.2024.116270

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title = "Comparison of MBT biotargets with MBT steel targets for matrix-assisted laser desorption/ionization time of flight mass spectrometry identifications of microorganisms in a clinical microbiology laboratory",

abstract = "MALDI-TOF MS identifications of microorganisms in a clinical laboratory were investigated, comparing steel targets with MBT Biotargets. By using MBT Biotargets, the score values of yeast identifications increased, whereas the score values of Gram-negative bacteria decreased. Switching to MBT Biotargets did not negatively impact overall frequencies of high confidence identifications.",

keywords = "Biotarget, Identification, MALDI-TOF MS, Steel target, Yeast",

author = "Schouten, {Robert K P} and Schweitzer, {Valentijn A} and {van Marm}, Sebastian and Rentenaar, {Rob J}",

note = "Publisher Copyright: {\textcopyright} 2024 The Author(s)",

year = "2024",

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doi = "10.1016/j.diagmicrobio.2024.116270",

language = "English",

volume = "109",

journal = "Diagnostic Microbiology and Infectious Disease",

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Schouten, RKP, Schweitzer, VA, van Marm, S & Rentenaar, RJ 2024, 'Comparison of MBT biotargets with MBT steel targets for matrix-assisted laser desorption/ionization time of flight mass spectrometry identifications of microorganisms in a clinical microbiology laboratory', Diagnostic Microbiology and Infectious Disease, vol. 109, no. 2, 116270. https://doi.org/10.1016/j.diagmicrobio.2024.116270

Comparison of MBT biotargets with MBT steel targets for matrix-assisted laser desorption/ionization time of flight mass spectrometry identifications of microorganisms in a clinical microbiology laboratory. / Schouten, Robert K P; Schweitzer, Valentijn A; van Marm, Sebastian et al.
In: Diagnostic Microbiology and Infectious Disease, Vol. 109, No. 2, 116270, 06.2024.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - Rentenaar, Rob J

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AB - MALDI-TOF MS identifications of microorganisms in a clinical laboratory were investigated, comparing steel targets with MBT Biotargets. By using MBT Biotargets, the score values of yeast identifications increased, whereas the score values of Gram-negative bacteria decreased. Switching to MBT Biotargets did not negatively impact overall frequencies of high confidence identifications.

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Schouten RKP, Schweitzer VA, van Marm S, Rentenaar RJ. Comparison of MBT biotargets with MBT steel targets for matrix-assisted laser desorption/ionization time of flight mass spectrometry identifications of microorganisms in a clinical microbiology laboratory. Diagnostic Microbiology and Infectious Disease. 2024 Jun;109(2):116270. doi: 10.1016/j.diagmicrobio.2024.116270

Comparison of MBT biotargets with MBT steel targets for matrix-assisted laser desorption/ionization time of flight mass spectrometry identifications of microorganisms in a clinical microbiology laboratory

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Keywords

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