TY - JOUR
T1 - Comparing Hip Dysplasia in Dogs and Humans
T2 - A Review
AU - Willemsen, Koen
AU - Möring, Michelle M.
AU - Harlianto, Netanja I.
AU - Tryfonidou, Marianna A.
AU - van der Wal, Bart C.H.
AU - Weinans, Harrie
AU - Meij, Björn P.
AU - Sakkers, Ralph J.B.
N1 - Funding Information:
KW and HW report a Governmental research grant from Interreg VA Flanders—The Netherlands program, during the conduct of the study; KW and HW report grants from the Smart industry project 15479 funded through governmental grant by NWO domain TTW, during the conduct of the study; MT, HW, and BM report funding from the Dutch Arthritis Society (LLP12/22). The funding sources played no role in the study design, data analysis and interpretation, nor drafting of the manuscript or the decision to submit it for publication.
Publisher Copyright:
Copyright © 2021 Willemsen, Möring, Harlianto, Tryfonidou, van der Wal, Weinans, Meij and Sakkers.
PY - 2021/12/15
Y1 - 2021/12/15
N2 - Hip dysplasia (HD) is common in both humans and dogs. This interconnection is because humans and dogs descended from a common ancestor and therefore have a similar anatomy at micro- and macroscopic levels. Furthermore, dogs are the animals of choice for testing new treatments for human hip dysplasia and orthopedic surgery in general. However, little literature exists comparing HD between the two species. Therefore, the aim of this review is to describe the anatomy, etiology, pathogenesis, diagnostics, and treatment of HD in humans and dogs. HD as an orthopedic condition has many common characteristics in terms of etiology and pathogenesis and most of the differences can be explained by the evolutionary differences between dogs and humans. Likewise, the treatment of HD shows many commonalities between humans and dogs. Conservative treatment and surgical interventions such as femoral osteotomy, pelvic osteotomy and total hip arthroplasty are very similar between humans and dogs. Therefore, future integration of knowledge and experiences for HD between dogs and humans could be beneficial for both species.
AB - Hip dysplasia (HD) is common in both humans and dogs. This interconnection is because humans and dogs descended from a common ancestor and therefore have a similar anatomy at micro- and macroscopic levels. Furthermore, dogs are the animals of choice for testing new treatments for human hip dysplasia and orthopedic surgery in general. However, little literature exists comparing HD between the two species. Therefore, the aim of this review is to describe the anatomy, etiology, pathogenesis, diagnostics, and treatment of HD in humans and dogs. HD as an orthopedic condition has many common characteristics in terms of etiology and pathogenesis and most of the differences can be explained by the evolutionary differences between dogs and humans. Likewise, the treatment of HD shows many commonalities between humans and dogs. Conservative treatment and surgical interventions such as femoral osteotomy, pelvic osteotomy and total hip arthroplasty are very similar between humans and dogs. Therefore, future integration of knowledge and experiences for HD between dogs and humans could be beneficial for both species.
KW - acetabulum
KW - comparative
KW - hip dysplasia
KW - one health
KW - translational
KW - treatment
UR - http://www.scopus.com/inward/record.url?scp=85121971895&partnerID=8YFLogxK
U2 - 10.3389/fvets.2021.791434
DO - 10.3389/fvets.2021.791434
M3 - Review article
AN - SCOPUS:85121971895
SN - 2297-1769
VL - 8
SP - 1
EP - 10
JO - Frontiers in veterinary science
JF - Frontiers in veterinary science
M1 - 791434
ER -