Combined Fc-protein- and Fc-glyco-engineering of scFv-Fc fusion proteins synergistically enhances CD16a binding but does not further enhance NK-cell mediated ADCC.

R. Repp; C. Kellner; A. Muskulus; M. Staudinger; S. Mohseni Nodehi; P. Glorius; D. Akramiene; M. Dechant; G.H. Fey; P.H.C. van Berkel; J.G.J. van de Winkel; P.W.H.I. Parren; T. Valerius; M. Gramatzki; M. Peipp

Combined Fc-protein- and Fc-glyco-engineering of scFv-Fc fusion proteins synergistically enhances CD16a binding but does not further enhance NK-cell mediated ADCC.

R. Repp
, C. Kellner
, A. Muskulus
, M. Staudinger
, S. Mohseni Nodehi
, P. Glorius
, D. Akramiene
, M. Dechant
, G.H. Fey
, P.H.C. van Berkel
, J.G.J. van de Winkel
, P.W.H.I. Parren
, T. Valerius
, M. Gramatzki
, M. Peipp

Center for Translational Immunology (CTI)

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	67-78
Number of pages	12
Journal	Journal of Immunological Methods
Volume	373
Issue number	1-2
Publication status	Published - 2011

Access to Document

http://www.ncbi.nlm.nih.gov/pubmed/21855548

Cite this

Repp, R., Kellner, C., Muskulus, A., Staudinger, M., Mohseni Nodehi, S., Glorius, P., Akramiene, D., Dechant, M., Fey, G. H., van Berkel, P. H. C., van de Winkel, J. G. J., Parren, P. W. H. I., Valerius, T., Gramatzki, M., & Peipp, M. (2011). Combined Fc-protein- and Fc-glyco-engineering of scFv-Fc fusion proteins synergistically enhances CD16a binding but does not further enhance NK-cell mediated ADCC. Journal of Immunological Methods, 373(1-2), 67-78. http://www.ncbi.nlm.nih.gov/pubmed/21855548

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title = "Combined Fc-protein- and Fc-glyco-engineering of scFv-Fc fusion proteins synergistically enhances CD16a binding but does not further enhance NK-cell mediated ADCC.",

author = "R. Repp and C. Kellner and A. Muskulus and M. Staudinger and \{Mohseni Nodehi\}, S. and P. Glorius and D. Akramiene and M. Dechant and G.H. Fey and \{van Berkel\}, P.H.C. and \{van de Winkel\}, J.G.J. and P.W.H.I. Parren and T. Valerius and M. Gramatzki and M. Peipp",

year = "2011",

language = "English",

volume = "373",

pages = "67--78",

journal = "Journal of Immunological Methods",

issn = "0022-1759",

publisher = "Elsevier",

number = "1-2",

}

Repp, R, Kellner, C, Muskulus, A, Staudinger, M, Mohseni Nodehi, S, Glorius, P, Akramiene, D, Dechant, M, Fey, GH, van Berkel, PHC, van de Winkel, JGJ, Parren, PWHI, Valerius, T, Gramatzki, M & Peipp, M 2011, 'Combined Fc-protein- and Fc-glyco-engineering of scFv-Fc fusion proteins synergistically enhances CD16a binding but does not further enhance NK-cell mediated ADCC.', Journal of Immunological Methods, vol. 373, no. 1-2, pp. 67-78. <http://www.ncbi.nlm.nih.gov/pubmed/21855548>

TY - JOUR

T1 - Combined Fc-protein- and Fc-glyco-engineering of scFv-Fc fusion proteins synergistically enhances CD16a binding but does not further enhance NK-cell mediated ADCC.

AU - Repp, R.

AU - Kellner, C.

AU - Muskulus, A.

AU - Staudinger, M.

AU - Mohseni Nodehi, S.

AU - Glorius, P.

AU - Akramiene, D.

AU - Dechant, M.

AU - Fey, G.H.

AU - van Berkel, P.H.C.

AU - van de Winkel, J.G.J.

AU - Parren, P.W.H.I.

AU - Valerius, T.

AU - Gramatzki, M.

AU - Peipp, M.

PY - 2011

Y1 - 2011

M3 - Article

SN - 0022-1759

VL - 373

SP - 67

EP - 78

JO - Journal of Immunological Methods

JF - Journal of Immunological Methods

IS - 1-2

ER -