Colonization with Pseudomonas aeruginosa in Patients Developing Ventilator-Associated Pneumonia

Dennis C. J. J. Bergmans, M. J M Bonten, Ellen E Stobberingh, Frank H. Van Tiel, Siebe Van Der Geest, Peter W de Leeuw, Carlo A. Gaillard

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Abstract

To determine routes of colonization and genotypic variation of Pseudomonas aeruginosa leading to ventilator-associated pneumonia, colonization of the rectum, stomach, oropharynx, and trachea was studied chronologically in 10 patients. Ninety-one isolates of P aeruginosa were genotyped; seven different genotypes were identified. Patients developing ventilator-associated pneumonia caused by P aeruginosa were colonized at multiple body sites and may be colonized with multiple genotypes. The upper respiratory tract is the predominant initial site of colonization with P aeruginosa.

Original languageEnglish
Pages (from-to)853-855
Number of pages3
JournalInfection control and hospital epidemiology
Volume19
Issue number11
Publication statusPublished - Nov 1998
Externally publishedYes

Keywords

  • Humans Oropharynx Pneumonia, Bacterial Prospective Studies Pseudomonas aeruginosa Rectum Respiration, Artificial Stomach Trachea

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