Coarctatio aortae: Een oorzaak van moeilijk behandelbare hypertensie

Timion A. Meijs; Danny A.J.P. van de Sande; Jesse Peek; A. Sander Limburg; Michiel Voskuil

Coarctatio aortae: Een oorzaak van moeilijk behandelbare hypertensie

Translated title of the contribution: Coarctation of the aorta as a cause of difficult-to-control hypertension

Timion A. Meijs, Danny A.J.P. van de Sande, Jesse Peek, A. Sander Limburg, Michiel Voskuil

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

BACKGROUND: Coarctation of the aorta (CoA) is a congenital narrowing of the proximal descending aorta, which may express itself as resistant hypertension in children and young adults.

CASE DESCRIPTION: A 25-year old female is known with hypertension for 9 years. Due to persistent hypertension despite telmisartan and amlodipine, she is referred to the outpatient clinic internal medicine, where a systolic murmur is heard. Consequently, she is referred to the cardiologist, who identifies a well-functioning bicuspid aortic valve and a severe CoA with extensive collateral circulation. The CoA is treated by stent implantation. After 7 months, the patient is normotensive without any antihypertensive medication.

CONCLUSION: Hypertension in children and young adults is a rare finding and often has a secondary cause. CoA is characterized by a combination of hypertension and a systolic blood pressure gradient between upper and lower extremities. Early diagnosis and treatment are crucial to avoid late cardiovascular complications.

Translated title of the contribution	Coarctation of the aorta as a cause of difficult-to-control hypertension
Original language	Dutch
Article number	D5417
Pages (from-to)	1-4
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	165
Publication status	Published - 9 Dec 2021

Cite this

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title = "Coarctatio aortae: Een oorzaak van moeilijk behandelbare hypertensie",

abstract = "BACKGROUND: Coarctation of the aorta (CoA) is a congenital narrowing of the proximal descending aorta, which may express itself as resistant hypertension in children and young adults.CASE DESCRIPTION: A 25-year old female is known with hypertension for 9 years. Due to persistent hypertension despite telmisartan and amlodipine, she is referred to the outpatient clinic internal medicine, where a systolic murmur is heard. Consequently, she is referred to the cardiologist, who identifies a well-functioning bicuspid aortic valve and a severe CoA with extensive collateral circulation. The CoA is treated by stent implantation. After 7 months, the patient is normotensive without any antihypertensive medication.CONCLUSION: Hypertension in children and young adults is a rare finding and often has a secondary cause. CoA is characterized by a combination of hypertension and a systolic blood pressure gradient between upper and lower extremities. Early diagnosis and treatment are crucial to avoid late cardiovascular complications.",

author = "Meijs, {Timion A.} and {van de Sande}, {Danny A.J.P.} and Jesse Peek and Limburg, {A. Sander} and Michiel Voskuil",

year = "2021",

month = dec,

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language = "Dutch",

volume = "165",

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journal = "Nederlands Tijdschrift voor Geneeskunde",

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T1 - Coarctatio aortae

T2 - Een oorzaak van moeilijk behandelbare hypertensie

AU - Meijs, Timion A.

AU - van de Sande, Danny A.J.P.

AU - Peek, Jesse

AU - Limburg, A. Sander

AU - Voskuil, Michiel

PY - 2021/12/9

Y1 - 2021/12/9

N2 - BACKGROUND: Coarctation of the aorta (CoA) is a congenital narrowing of the proximal descending aorta, which may express itself as resistant hypertension in children and young adults.CASE DESCRIPTION: A 25-year old female is known with hypertension for 9 years. Due to persistent hypertension despite telmisartan and amlodipine, she is referred to the outpatient clinic internal medicine, where a systolic murmur is heard. Consequently, she is referred to the cardiologist, who identifies a well-functioning bicuspid aortic valve and a severe CoA with extensive collateral circulation. The CoA is treated by stent implantation. After 7 months, the patient is normotensive without any antihypertensive medication.CONCLUSION: Hypertension in children and young adults is a rare finding and often has a secondary cause. CoA is characterized by a combination of hypertension and a systolic blood pressure gradient between upper and lower extremities. Early diagnosis and treatment are crucial to avoid late cardiovascular complications.

AB - BACKGROUND: Coarctation of the aorta (CoA) is a congenital narrowing of the proximal descending aorta, which may express itself as resistant hypertension in children and young adults.CASE DESCRIPTION: A 25-year old female is known with hypertension for 9 years. Due to persistent hypertension despite telmisartan and amlodipine, she is referred to the outpatient clinic internal medicine, where a systolic murmur is heard. Consequently, she is referred to the cardiologist, who identifies a well-functioning bicuspid aortic valve and a severe CoA with extensive collateral circulation. The CoA is treated by stent implantation. After 7 months, the patient is normotensive without any antihypertensive medication.CONCLUSION: Hypertension in children and young adults is a rare finding and often has a secondary cause. CoA is characterized by a combination of hypertension and a systolic blood pressure gradient between upper and lower extremities. Early diagnosis and treatment are crucial to avoid late cardiovascular complications.

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SN - 0028-2162

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JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

M1 - D5417

ER -

Coarctatio aortae: Een oorzaak van moeilijk behandelbare hypertensie

Abstract

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