CO
                        2
                        -laser therapy in patients with vulvar intraepithelial neoplasia

Th J.M. Helmerhorst; C. H. van der Vaart; G. H. Dijkhuizen; J. J. Calame; P. Kenemans; J. G. Stolk

doi:10.1016/0028-2243(90)90018-V

CO ₂ -laser therapy in patients with vulvar intraepithelial neoplasia

Th J.M. Helmerhorst^*
, C. H. van der Vaart
, G. H. Dijkhuizen
, J. J. Calame
, P. Kenemans
, J. G. Stolk

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

4 Citations (Scopus)

Abstract

It is generally accepted to consider vulvar intraepithelial neoplasia grade III(VIN III) a premalignant condition. The lesion is more frequently diagnosed in younger patients. Conventional surgical treatment is often mutilating and recurrence rates have been reported of approximately 30%. Laser vaporization is a promising alternative therapy. Ten patients with VIN III were treated with CO ₂ laser. Two patients were retreated with laser for residual disease, and two patients for recurrent disease. One failure was observed, and one patient was off-study. In all patients excellent cosmetic results were obtained. Laser vaporization appears to be an effective and nonmutilating therapy, and preferable for young VIN patients.

Original language	English
Pages (from-to)	149-155
Number of pages	7
Journal	European Journal of Obstetrics and Gynecology and Reproductive Biology
Volume	34
Issue number	1-2
DOIs	https://doi.org/10.1016/0028-2243(90)90018-V
Publication status	Published - 1 Jan 1990

Keywords

Laser
Vulvar intraepithelial neoplasia

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10.1016/0028-2243(90)90018-V

Cite this

@article{4accabad557947b49d54ab848000e1f9,

title = "CO 2 -laser therapy in patients with vulvar intraepithelial neoplasia",

abstract = " It is generally accepted to consider vulvar intraepithelial neoplasia grade III(VIN III) a premalignant condition. The lesion is more frequently diagnosed in younger patients. Conventional surgical treatment is often mutilating and recurrence rates have been reported of approximately 30\%. Laser vaporization is a promising alternative therapy. Ten patients with VIN III were treated with CO 2 laser. Two patients were retreated with laser for residual disease, and two patients for recurrent disease. One failure was observed, and one patient was off-study. In all patients excellent cosmetic results were obtained. Laser vaporization appears to be an effective and nonmutilating therapy, and preferable for young VIN patients.",

keywords = "Laser, Vulvar intraepithelial neoplasia",

author = "Helmerhorst, \{Th J.M.\} and \{van der Vaart\}, \{C. H.\} and Dijkhuizen, \{G. H.\} and Calame, \{J. J.\} and P. Kenemans and Stolk, \{J. G.\}",

year = "1990",

month = jan,

day = "1",

doi = "10.1016/0028-2243(90)90018-V",

language = "English",

volume = "34",

pages = "149--155",

journal = "European Journal of Obstetrics and Gynecology and Reproductive Biology",

issn = "0028-2243",

publisher = "Elsevier Ireland Ltd",

number = "1-2",

}

CO ₂ -laser therapy in patients with vulvar intraepithelial neoplasia. / Helmerhorst, Th J.M.; van der Vaart, C. H.; Dijkhuizen, G. H. et al.
In: European Journal of Obstetrics and Gynecology and Reproductive Biology, Vol. 34, No. 1-2, 01.01.1990, p. 149-155.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - CO 2 -laser therapy in patients with vulvar intraepithelial neoplasia

AU - Helmerhorst, Th J.M.

AU - van der Vaart, C. H.

AU - Dijkhuizen, G. H.

AU - Calame, J. J.

AU - Kenemans, P.

AU - Stolk, J. G.

PY - 1990/1/1

Y1 - 1990/1/1

N2 - It is generally accepted to consider vulvar intraepithelial neoplasia grade III(VIN III) a premalignant condition. The lesion is more frequently diagnosed in younger patients. Conventional surgical treatment is often mutilating and recurrence rates have been reported of approximately 30%. Laser vaporization is a promising alternative therapy. Ten patients with VIN III were treated with CO 2 laser. Two patients were retreated with laser for residual disease, and two patients for recurrent disease. One failure was observed, and one patient was off-study. In all patients excellent cosmetic results were obtained. Laser vaporization appears to be an effective and nonmutilating therapy, and preferable for young VIN patients.

AB - It is generally accepted to consider vulvar intraepithelial neoplasia grade III(VIN III) a premalignant condition. The lesion is more frequently diagnosed in younger patients. Conventional surgical treatment is often mutilating and recurrence rates have been reported of approximately 30%. Laser vaporization is a promising alternative therapy. Ten patients with VIN III were treated with CO 2 laser. Two patients were retreated with laser for residual disease, and two patients for recurrent disease. One failure was observed, and one patient was off-study. In all patients excellent cosmetic results were obtained. Laser vaporization appears to be an effective and nonmutilating therapy, and preferable for young VIN patients.

KW - Laser

KW - Vulvar intraepithelial neoplasia

UR - https://www.scopus.com/pages/publications/0024985263

U2 - 10.1016/0028-2243(90)90018-V

DO - 10.1016/0028-2243(90)90018-V

M3 - Article

C2 - 2303148

AN - SCOPUS:0024985263

SN - 0028-2243

VL - 34

SP - 149

EP - 155

JO - European Journal of Obstetrics and Gynecology and Reproductive Biology

JF - European Journal of Obstetrics and Gynecology and Reproductive Biology

IS - 1-2

ER -

CO ₂ -laser therapy in patients with vulvar intraepithelial neoplasia

Abstract

Keywords

Access to Document

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