TY - JOUR
T1 - Clinical practice guidelines on the treatment of patients with cleft lip, alveolus, and palate
T2 - An executive summary
AU - Mink van der Molen, Aebele B.
AU - van Breugel, Johanna M.M.
AU - Janssen, Nard G.
AU - Admiraal, Ronald J.C.
AU - van Adrichem, Leon N.A.
AU - Bierenbroodspot, Frank
AU - Bittermann, Dirk
AU - van den Boogaard, Marie José H.
AU - Broos, Pieter H.
AU - Dijkstra‐putkamer, Janet J.M.
AU - van Gemert‐Schriks, Martine C.M.
AU - Kortlever, Andrea L.J.
AU - Mouës‐vink, Chantal M.
AU - Swanenburg de Veye, Henriette F.N.
AU - van Tol‐Verbeek, Nanouk
AU - Vermeij‐keers, Christl
AU - de Wilde, Hester
AU - Kuijpers‐jagtman, Anne Marie
N1 - Funding Information:
Funding: The guideline development was partly funded by the Dutch Quality Fund for Medical Specialists for the Netherlands Society for Plastic and Reconstructive Surgery with co‐funding from the Dutch Association for Oto‐rhino‐laryngology and Surgery of the Head and Neck, the Dutch Association of Orthodontists, the Dutch Scientific Association of Dentists, and the Dutch Association for Oral and Maxillofacial Surgery. Additional funding will be available to keep these CPGs up to date in the near future. The translation to English was supported by the European Reference Network for rare and/or complex craniofacial anomalies and ear, nose, and throat (ENT) disorders (www.ern‐cranio.eu). No funding has been received to cover the article processing fee (which was waved).
Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/11/1
Y1 - 2021/11/1
N2 - Significant treatment variation exists in the Netherlands between teams treating patients with cleft lip, alveolus, and/or palate, resulting in a confusing and undesirable situation for patients, parents, and practitioners. Therefore, to optimize cleft care, clinical practice guidelines (CPGs) were developed. The aim of this report is to describe CPG development, share the main recommendations, and indicate knowledge gaps regarding cleft care. Together with patients and parents, a multidisciplinary working group of representatives from all relevant disciplines assisted by two experienced epidemiologists identified the topics to be addressed in the CPGs. Searching the Medline, Embase, and Cochrane Library databases identified 5157 articles, 60 of which remained after applying inclusion and exclusion criteria. We rated the quality of the evidence from moderate to very low. The working group formulated 71 recommendations regarding genetic testing, feeding, lip and palate closure, hearing, hypernasality, bone grafting, orthodontics, psychosocial guidance, dentistry, osteotomy versus distraction, and rhinoplasty. The final CPGs were obtained after review by all stakeholders and allow cleft teams to base their treatment on current knowledge. With high-quality evidence lacking, the need for additional high‐quality studies has become apparent.
AB - Significant treatment variation exists in the Netherlands between teams treating patients with cleft lip, alveolus, and/or palate, resulting in a confusing and undesirable situation for patients, parents, and practitioners. Therefore, to optimize cleft care, clinical practice guidelines (CPGs) were developed. The aim of this report is to describe CPG development, share the main recommendations, and indicate knowledge gaps regarding cleft care. Together with patients and parents, a multidisciplinary working group of representatives from all relevant disciplines assisted by two experienced epidemiologists identified the topics to be addressed in the CPGs. Searching the Medline, Embase, and Cochrane Library databases identified 5157 articles, 60 of which remained after applying inclusion and exclusion criteria. We rated the quality of the evidence from moderate to very low. The working group formulated 71 recommendations regarding genetic testing, feeding, lip and palate closure, hearing, hypernasality, bone grafting, orthodontics, psychosocial guidance, dentistry, osteotomy versus distraction, and rhinoplasty. The final CPGs were obtained after review by all stakeholders and allow cleft teams to base their treatment on current knowledge. With high-quality evidence lacking, the need for additional high‐quality studies has become apparent.
KW - Cleft lip, alveolus and palate
KW - Clinical practice guideline
KW - Quality of health care
KW - Recommendation clinical care
KW - Treatment
UR - http://www.scopus.com/inward/record.url?scp=85117170947&partnerID=8YFLogxK
U2 - 10.3390/jcm10214813
DO - 10.3390/jcm10214813
M3 - Article
AN - SCOPUS:85117170947
SN - 2077-0383
VL - 10
JO - Journal of Clinical medicine
JF - Journal of Clinical medicine
IS - 21
M1 - 4813
ER -