Clinical evidence on haemodiafiltration

Peter J. Blankestijn; Muriel P. Grooteman; Menso J. Nube; Michiel L. Bots

doi:10.1093/ndt/gfy218

Clinical evidence on haemodiafiltration

Peter J. Blankestijn^*
, Muriel P. Grooteman
, Menso J. Nube
, Michiel L. Bots

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

3 Downloads (Pure)

Abstract

Haemodiafiltration (HDF) combines diffusive and convective solute removal in a single treatment session. HDF provides a greater removal of higher molecular weight uraemic retention solutes than conventional high-flux haemodialysis (HD). Recently completed randomized clinical trials suggest better patient survival with online HDF. The treatment is mainly used in Europe and Japan. This review gives a brief overview of the presently available evidence of the effects of HDF on clinical end points, it speculates on possible mechanisms of a beneficial effect of HDF as compared with standard HD and ends with some perspectives for the future.

Original language	English
Pages (from-to)	iii53-iii58
Journal	Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Volume	33
Issue number	suppl_3
DOIs	https://doi.org/10.1093/ndt/gfy218 https://doi.org/10.1093/ndt/gfy218
Publication status	Published - 1 Oct 2018

Keywords

chronic hemodialysis
clinical outcome
hemodiafiltration
online hemodiafiltration
review

Access to Document

ClinicalFinal published version, 208 KB

Cite this

@article{ec65ee6092774d61ba672d8a1067373b,

title = "Clinical evidence on haemodiafiltration",

abstract = "Haemodiafiltration (HDF) combines diffusive and convective solute removal in a single treatment session. HDF provides a greater removal of higher molecular weight uraemic retention solutes than conventional high-flux haemodialysis (HD). Recently completed randomized clinical trials suggest better patient survival with online HDF. The treatment is mainly used in Europe and Japan. This review gives a brief overview of the presently available evidence of the effects of HDF on clinical end points, it speculates on possible mechanisms of a beneficial effect of HDF as compared with standard HD and ends with some perspectives for the future.",

keywords = "chronic hemodialysis, clinical outcome, hemodiafiltration, online hemodiafiltration, review",

author = "Blankestijn, \{Peter J.\} and Grooteman, \{Muriel P.\} and Nube, \{Menso J.\} and Bots, \{Michiel L.\}",

note = "Publisher Copyright: {\textcopyright} 2018 The Author(s).",

year = "2018",

month = oct,

day = "1",

doi = "10.1093/ndt/gfy218",

language = "English",

volume = "33",

pages = "iii53--iii58",

journal = "Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association",

issn = "0931-0509",

publisher = "Oxford University Press",

number = "suppl\_3",

}

Clinical evidence on haemodiafiltration. / Blankestijn, Peter J.; Grooteman, Muriel P.; Nube, Menso J. et al.
In: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 33, No. suppl_3, 01.10.2018, p. iii53-iii58.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Clinical evidence on haemodiafiltration

AU - Blankestijn, Peter J.

AU - Grooteman, Muriel P.

AU - Nube, Menso J.

AU - Bots, Michiel L.

PY - 2018/10/1

Y1 - 2018/10/1

N2 - Haemodiafiltration (HDF) combines diffusive and convective solute removal in a single treatment session. HDF provides a greater removal of higher molecular weight uraemic retention solutes than conventional high-flux haemodialysis (HD). Recently completed randomized clinical trials suggest better patient survival with online HDF. The treatment is mainly used in Europe and Japan. This review gives a brief overview of the presently available evidence of the effects of HDF on clinical end points, it speculates on possible mechanisms of a beneficial effect of HDF as compared with standard HD and ends with some perspectives for the future.

AB - Haemodiafiltration (HDF) combines diffusive and convective solute removal in a single treatment session. HDF provides a greater removal of higher molecular weight uraemic retention solutes than conventional high-flux haemodialysis (HD). Recently completed randomized clinical trials suggest better patient survival with online HDF. The treatment is mainly used in Europe and Japan. This review gives a brief overview of the presently available evidence of the effects of HDF on clinical end points, it speculates on possible mechanisms of a beneficial effect of HDF as compared with standard HD and ends with some perspectives for the future.

KW - chronic hemodialysis

KW - clinical outcome

KW - hemodiafiltration

KW - online hemodiafiltration

KW - review

UR - https://www.scopus.com/pages/publications/85054413147

U2 - 10.1093/ndt/gfy218

DO - 10.1093/ndt/gfy218

M3 - Article

C2 - 30281128

SN - 0931-0509

VL - 33

SP - iii53-iii58

JO - Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

JF - Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

IS - suppl_3

ER -

Clinical evidence on haemodiafiltration

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this