Clinical and immunologic effects of maraviroc in progressive multifocal leukoencephalopathy

Ananja Middel; Joop E. Arends; Steven F L Van Lelyveld; Sigrid Otto; Rob Schuurman; Catharina J M Frijns; Kiki Tesselaar; Andy I M Hoepelman

doi:10.1212/WNL.0000000000001713

Clinical and immunologic effects of maraviroc in progressive multifocal leukoencephalopathy

Ananja Middel, Joop E. Arends^*, Steven F L Van Lelyveld, Sigrid Otto, Rob Schuurman, Catharina J M Frijns, Kiki Tesselaar, Andy I M Hoepelman

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Progressive multifocal leukoencephalopathy (PML) is a rare but generally fatal disease due to JC virus (JCV) reactivation, mainly occurring in immunosuppressed patients.(1) Therapeutic options are limited to blocking glial cell infection by mirtazapine or restoring cell-mediated immunity to acquire viral control.(2)

Original language	English
Pages (from-to)	104-106
Number of pages	3
Journal	Neurology
Volume	85
Issue number	1
DOIs	https://doi.org/10.1212/WNL.0000000000001713
Publication status	Published - 7 Jul 2015

Keywords

RECONSTITUTION INFLAMMATORY SYNDROME
JC VIRUS

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title = "Clinical and immunologic effects of maraviroc in progressive multifocal leukoencephalopathy",

abstract = "Progressive multifocal leukoencephalopathy (PML) is a rare but generally fatal disease due to JC virus (JCV) reactivation, mainly occurring in immunosuppressed patients.(1) Therapeutic options are limited to blocking glial cell infection by mirtazapine or restoring cell-mediated immunity to acquire viral control.(2)",

keywords = "RECONSTITUTION INFLAMMATORY SYNDROME, JC VIRUS",

author = "Ananja Middel and Arends, {Joop E.} and {Van Lelyveld}, {Steven F L} and Sigrid Otto and Rob Schuurman and Frijns, {Catharina J M} and Kiki Tesselaar and Hoepelman, {Andy I M}",

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AU - Middel, Ananja

AU - Arends, Joop E.

AU - Van Lelyveld, Steven F L

AU - Otto, Sigrid

AU - Schuurman, Rob

AU - Frijns, Catharina J M

AU - Tesselaar, Kiki

AU - Hoepelman, Andy I M

PY - 2015/7/7

Y1 - 2015/7/7

N2 - Progressive multifocal leukoencephalopathy (PML) is a rare but generally fatal disease due to JC virus (JCV) reactivation, mainly occurring in immunosuppressed patients.(1) Therapeutic options are limited to blocking glial cell infection by mirtazapine or restoring cell-mediated immunity to acquire viral control.(2)

AB - Progressive multifocal leukoencephalopathy (PML) is a rare but generally fatal disease due to JC virus (JCV) reactivation, mainly occurring in immunosuppressed patients.(1) Therapeutic options are limited to blocking glial cell infection by mirtazapine or restoring cell-mediated immunity to acquire viral control.(2)

KW - RECONSTITUTION INFLAMMATORY SYNDROME

KW - JC VIRUS

U2 - 10.1212/WNL.0000000000001713

DO - 10.1212/WNL.0000000000001713

M3 - Article

C2 - 26041329

SN - 0028-3878

VL - 85

SP - 104

EP - 106

JO - Neurology

JF - Neurology

IS - 1

ER -

Clinical and immunologic effects of maraviroc in progressive multifocal leukoencephalopathy

Abstract

Keywords

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