Chronic Idiopathic Axonal Polyneuropathy

G. M. van der Star; A. F.J.E. Vrancken; Notermans N.C. Notermans

doi:10.1016/B978-0-323-95702-1.00329-8

Chronic Idiopathic Axonal Polyneuropathy

G. M. van der Star
, A. F.J.E. Vrancken
, Notermans N.C. Notermans

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

Abstract

Chronic idiopathic axonal polyneuropathy (CIAP) comprises around one-third of chronic polyneuropathy patients, with no risk factor or cause identified after extensive diagnostic workup. It is characterized by predominantly sensory symptoms and signs, in a length-dependent distribution, following a slowly progressive course and patients remain ambulant. Diagnostic evaluation includes laboratory tests to rule out other risk factors and causes and nerve conduction studies to rule out demyelinating polyneuropathy. There is no evidence-based therapy to reduce or halt disease progression, but management may involve assistive walking devices and symptomatic pain treatment.

Original language	English
Title of host publication	Encyclopedia of the Neurological Sciences
Publisher	Elsevier
Pages	V4:689-V4:692
ISBN (Electronic)	9780323957021
ISBN (Print)	9780323957052
DOIs	https://doi.org/10.1016/B978-0-323-95702-1.00329-8
Publication status	Published - 1 Jan 2025

Keywords

Axons/pathology∗ (MeSH term)
Cryptogenic
Diagnosis (MeSH term)
Humans (MeSH term)
Idiopathic
Polyneuropathies (MeSH term)

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10.1016/B978-0-323-95702-1.00329-8

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abstract = "Chronic idiopathic axonal polyneuropathy (CIAP) comprises around one-third of chronic polyneuropathy patients, with no risk factor or cause identified after extensive diagnostic workup. It is characterized by predominantly sensory symptoms and signs, in a length-dependent distribution, following a slowly progressive course and patients remain ambulant. Diagnostic evaluation includes laboratory tests to rule out other risk factors and causes and nerve conduction studies to rule out demyelinating polyneuropathy. There is no evidence-based therapy to reduce or halt disease progression, but management may involve assistive walking devices and symptomatic pain treatment.",

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KW - Axons/pathology∗ (MeSH term)

KW - Cryptogenic

KW - Diagnosis (MeSH term)

KW - Humans (MeSH term)

KW - Idiopathic

KW - Polyneuropathies (MeSH term)

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PB - Elsevier

ER -

Chronic Idiopathic Axonal Polyneuropathy

Abstract

Keywords

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