TY - JOUR
T1 - Changes in adherence of respiratory pathogens to HEp-2 cells induced by subinhibitory concentrations of sparfloxacin, ciprofloxacin, and trimethoprim
AU - Visser, M. R.
AU - Beumer, H.
AU - Hoepelman, A. I.M.
AU - Rozenberg-Arska, M.
AU - Verhoef, J.
PY - 1993/1/1
Y1 - 1993/1/1
N2 - Preincubation with subinhibitory concentrations of sparfloxacin, ciprofloxacin, and trimethoprim decreased the adherence of the respiratory pathogens Klebsiella pneumoniae, Haemophilus influenzae, and Moraxalla (Branhamella) catarrhalis to human larynx carcinoma HEp-2 cells. Subinhibitory concentrations of sparfloxacin did not change the adherence of Pseudomonas aeruginosa or Streptococcus pneumoniae 15.62, but adhesion of S. pneumoniae 15.42 was significantly enhanced by subinhibitory antimicrobial concentrations.
AB - Preincubation with subinhibitory concentrations of sparfloxacin, ciprofloxacin, and trimethoprim decreased the adherence of the respiratory pathogens Klebsiella pneumoniae, Haemophilus influenzae, and Moraxalla (Branhamella) catarrhalis to human larynx carcinoma HEp-2 cells. Subinhibitory concentrations of sparfloxacin did not change the adherence of Pseudomonas aeruginosa or Streptococcus pneumoniae 15.62, but adhesion of S. pneumoniae 15.42 was significantly enhanced by subinhibitory antimicrobial concentrations.
UR - http://www.scopus.com/inward/record.url?scp=0027522989&partnerID=8YFLogxK
U2 - 10.1128/AAC.37.4.885
DO - 10.1128/AAC.37.4.885
M3 - Comment/Letter to the editor
C2 - 8388203
AN - SCOPUS:0027522989
SN - 0066-4804
VL - 37
SP - 885
EP - 888
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 4
ER -