Cerebral ventricular dilation in congenital myotonic dystrophy

R. Regev; L. S. de Vries; J. Z. Heckmatt; V. Dubowitz

doi:10.1016/S0022-3476(87)80456-0

Cerebral ventricular dilation in congenital myotonic dystrophy

R. Regev
, L. S. de Vries
, J. Z. Heckmatt
, V. Dubowitz^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

23 Citations (Scopus)

Abstract

Ultrasonography or computed tomography scanning of the brain was performed in 10 infants with congenital myotonic dystrophy between the age of 1 day and 2 months, and showed intracranial abnormalites in all. Ventricular dilation was diagnosed in eight (80%), subarachnoid hemorrhage in one, and white matter infarcts in one. The common finding of ventricular dilation is probably related to developmental brain abnormality dating back to fetal life, because it was already present in three infants scanned on the first day of life. Neonatal asphyxia was present in seven infants, associated with intraventricular hemorrhage in two. The relationship between these changes and mental retardation, which is a common feature in this disease, is unclear.

Original language	English
Pages (from-to)	372-376
Number of pages	5
Journal	The Journal of Pediatrics
Volume	111
Issue number	3
DOIs	https://doi.org/10.1016/S0022-3476(87)80456-0
Publication status	Published - 1 Jan 1987

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title = "Cerebral ventricular dilation in congenital myotonic dystrophy",

abstract = "Ultrasonography or computed tomography scanning of the brain was performed in 10 infants with congenital myotonic dystrophy between the age of 1 day and 2 months, and showed intracranial abnormalites in all. Ventricular dilation was diagnosed in eight (80\%), subarachnoid hemorrhage in one, and white matter infarcts in one. The common finding of ventricular dilation is probably related to developmental brain abnormality dating back to fetal life, because it was already present in three infants scanned on the first day of life. Neonatal asphyxia was present in seven infants, associated with intraventricular hemorrhage in two. The relationship between these changes and mental retardation, which is a common feature in this disease, is unclear.",

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AU - Regev, R.

AU - de Vries, L. S.

AU - Heckmatt, J. Z.

AU - Dubowitz, V.

PY - 1987/1/1

Y1 - 1987/1/1

N2 - Ultrasonography or computed tomography scanning of the brain was performed in 10 infants with congenital myotonic dystrophy between the age of 1 day and 2 months, and showed intracranial abnormalites in all. Ventricular dilation was diagnosed in eight (80%), subarachnoid hemorrhage in one, and white matter infarcts in one. The common finding of ventricular dilation is probably related to developmental brain abnormality dating back to fetal life, because it was already present in three infants scanned on the first day of life. Neonatal asphyxia was present in seven infants, associated with intraventricular hemorrhage in two. The relationship between these changes and mental retardation, which is a common feature in this disease, is unclear.

AB - Ultrasonography or computed tomography scanning of the brain was performed in 10 infants with congenital myotonic dystrophy between the age of 1 day and 2 months, and showed intracranial abnormalites in all. Ventricular dilation was diagnosed in eight (80%), subarachnoid hemorrhage in one, and white matter infarcts in one. The common finding of ventricular dilation is probably related to developmental brain abnormality dating back to fetal life, because it was already present in three infants scanned on the first day of life. Neonatal asphyxia was present in seven infants, associated with intraventricular hemorrhage in two. The relationship between these changes and mental retardation, which is a common feature in this disease, is unclear.

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JO - The Journal of Pediatrics

JF - The Journal of Pediatrics

IS - 3

ER -

Cerebral ventricular dilation in congenital myotonic dystrophy

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