TY - JOUR
T1 - Cerebral ventricular dilation in congenital myotonic dystrophy
AU - Regev, R.
AU - de Vries, L. S.
AU - Heckmatt, J. Z.
AU - Dubowitz, V.
PY - 1987/1/1
Y1 - 1987/1/1
N2 - Ultrasonography or computed tomography scanning of the brain was performed in 10 infants with congenital myotonic dystrophy between the age of 1 day and 2 months, and showed intracranial abnormalites in all. Ventricular dilation was diagnosed in eight (80%), subarachnoid hemorrhage in one, and white matter infarcts in one. The common finding of ventricular dilation is probably related to developmental brain abnormality dating back to fetal life, because it was already present in three infants scanned on the first day of life. Neonatal asphyxia was present in seven infants, associated with intraventricular hemorrhage in two. The relationship between these changes and mental retardation, which is a common feature in this disease, is unclear.
AB - Ultrasonography or computed tomography scanning of the brain was performed in 10 infants with congenital myotonic dystrophy between the age of 1 day and 2 months, and showed intracranial abnormalites in all. Ventricular dilation was diagnosed in eight (80%), subarachnoid hemorrhage in one, and white matter infarcts in one. The common finding of ventricular dilation is probably related to developmental brain abnormality dating back to fetal life, because it was already present in three infants scanned on the first day of life. Neonatal asphyxia was present in seven infants, associated with intraventricular hemorrhage in two. The relationship between these changes and mental retardation, which is a common feature in this disease, is unclear.
UR - http://www.scopus.com/inward/record.url?scp=0023628784&partnerID=8YFLogxK
U2 - 10.1016/S0022-3476(87)80456-0
DO - 10.1016/S0022-3476(87)80456-0
M3 - Article
C2 - 3305848
AN - SCOPUS:0023628784
SN - 0022-3476
VL - 111
SP - 372
EP - 376
JO - The Journal of Pediatrics
JF - The Journal of Pediatrics
IS - 3
ER -