Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

Laurens E Franssen; Inger S Nijhof; Suzana Couto; Mark-David Levin; Gerard M J Bos; Annemiek Broijl; Saskia K Klein; Yan Ren; Maria Wang; Harry R Koene; Andries C Bloem; Aart Beeker; Laura M Faber; Ellen van der Spek; Reinier Raymakers; Roos J Leguit; Pieter Sonneveld; Sonja Zweegman; Henk Lokhorst; Tuna Mutis; Anjan Thakurta; Xiaozhong Qian; Niels W C J van de Donk

doi:10.3324/haematol.2017.186601

Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

Laurens E Franssen
, Inger S Nijhof
, Suzana Couto
, Mark-David Levin
, Gerard M J Bos
, Annemiek Broijl
, Saskia K Klein
, Yan Ren
, Maria Wang
, Harry R Koene
, Andries C Bloem
, Aart Beeker
, Laura M Faber
, Ellen van der Spek
, Reinier Raymakers
, Roos J Leguit
, Pieter Sonneveld
, Sonja Zweegman
, Henk Lokhorst
, Tuna Mutis

Anjan Thakurta, Xiaozhong Qian, Niels W C J van de Donk

Research output: Contribution to journal › Article › Academic › peer-review

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Original language	English
Pages (from-to)	e368-e371
Journal	Haematologica
Volume	103
Issue number	8
DOIs	https://doi.org/10.3324/haematol.2017.186601
Publication status	Published - Aug 2018

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10.3324/haematol.2017.186601

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Franssen, L. E., Nijhof, I. S., Couto, S., Levin, M.-D., Bos, G. M. J., Broijl, A., Klein, S. K., Ren, Y., Wang, M., Koene, H. R., Bloem, A. C., Beeker, A., Faber, L. M., van der Spek, E., Raymakers, R., Leguit, R. J., Sonneveld, P., Zweegman, S., Lokhorst, H., ... van de Donk, N. W. C. J. (2018). Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients. Haematologica, 103(8), e368-e371. https://doi.org/10.3324/haematol.2017.186601

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title = "Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients",

author = "Franssen, \{Laurens E\} and Nijhof, \{Inger S\} and Suzana Couto and Mark-David Levin and Bos, \{Gerard M J\} and Annemiek Broijl and Klein, \{Saskia K\} and Yan Ren and Maria Wang and Koene, \{Harry R\} and Bloem, \{Andries C\} and Aart Beeker and Faber, \{Laura M\} and \{van der Spek\}, Ellen and Reinier Raymakers and Leguit, \{Roos J\} and Pieter Sonneveld and Sonja Zweegman and Henk Lokhorst and Tuna Mutis and Anjan Thakurta and Xiaozhong Qian and \{van de Donk\}, \{Niels W C J\}",

year = "2018",

month = aug,

doi = "10.3324/haematol.2017.186601",

language = "English",

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Franssen, LE, Nijhof, IS, Couto, S, Levin, M-D, Bos, GMJ, Broijl, A, Klein, SK, Ren, Y, Wang, M, Koene, HR, Bloem, AC, Beeker, A, Faber, LM, van der Spek, E, Raymakers, R, Leguit, RJ, Sonneveld, P, Zweegman, S, Lokhorst, H, Mutis, T, Thakurta, A, Qian, X & van de Donk, NWCJ 2018, 'Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients', Haematologica, vol. 103, no. 8, pp. e368-e371. https://doi.org/10.3324/haematol.2017.186601

TY - JOUR

T1 - Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

AU - Franssen, Laurens E

AU - Nijhof, Inger S

AU - Couto, Suzana

AU - Levin, Mark-David

AU - Bos, Gerard M J

AU - Broijl, Annemiek

AU - Klein, Saskia K

AU - Ren, Yan

AU - Wang, Maria

AU - Koene, Harry R

AU - Bloem, Andries C

AU - Beeker, Aart

AU - Faber, Laura M

AU - van der Spek, Ellen

AU - Raymakers, Reinier

AU - Leguit, Roos J

AU - Sonneveld, Pieter

AU - Zweegman, Sonja

AU - Lokhorst, Henk

AU - Mutis, Tuna

AU - Thakurta, Anjan

AU - Qian, Xiaozhong

AU - van de Donk, Niels W C J

PY - 2018/8

Y1 - 2018/8

U2 - 10.3324/haematol.2017.186601

DO - 10.3324/haematol.2017.186601

M3 - Article

C2 - 29545338

SN - 0390-6078

VL - 103

SP - e368-e371

JO - Haematologica

JF - Haematologica

IS - 8

ER -