Cell-mediated cytotoxicity targets on canine endothelial cells

G. Groenewegen; W. A. Buurman; G. M.A.A. Jeunhomme; G. Kootstra

Cell-mediated cytotoxicity targets on canine endothelial cells

G. Groenewegen, W. A. Buurman, G. M.A.A. Jeunhomme, G. Kootstra

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Abstract

The authors present data of lysis of endothelial cells in vitro by CTL generated in MLC measured with a ⁵¹Cr-release assay. To compare determinants recognized by CTL on endothelial cells and PHA blasts, cold target inhibition experiments have been performed. It appeared that arterial endothelial cells (AEC) are recognized by CTL through class I antigens, as are PHA blasts; however, venous endothelial cells (VEC) appeared to be recognized through determinants not recognized on PHA blasts.

Original language	English
Pages (from-to)	289-291
Number of pages	3
Journal	Transplantation Proceedings
Volume	15
Issue number	1
Publication status	Published - 1 Jan 1983

Cite this

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title = "Cell-mediated cytotoxicity targets on canine endothelial cells",

abstract = "The authors present data of lysis of endothelial cells in vitro by CTL generated in MLC measured with a 51Cr-release assay. To compare determinants recognized by CTL on endothelial cells and PHA blasts, cold target inhibition experiments have been performed. It appeared that arterial endothelial cells (AEC) are recognized by CTL through class I antigens, as are PHA blasts; however, venous endothelial cells (VEC) appeared to be recognized through determinants not recognized on PHA blasts.",

author = "G. Groenewegen and Buurman, {W. A.} and Jeunhomme, {G. M.A.A.} and G. Kootstra",

year = "1983",

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AU - Groenewegen, G.

AU - Buurman, W. A.

AU - Jeunhomme, G. M.A.A.

AU - Kootstra, G.

PY - 1983/1/1

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N2 - The authors present data of lysis of endothelial cells in vitro by CTL generated in MLC measured with a 51Cr-release assay. To compare determinants recognized by CTL on endothelial cells and PHA blasts, cold target inhibition experiments have been performed. It appeared that arterial endothelial cells (AEC) are recognized by CTL through class I antigens, as are PHA blasts; however, venous endothelial cells (VEC) appeared to be recognized through determinants not recognized on PHA blasts.

AB - The authors present data of lysis of endothelial cells in vitro by CTL generated in MLC measured with a 51Cr-release assay. To compare determinants recognized by CTL on endothelial cells and PHA blasts, cold target inhibition experiments have been performed. It appeared that arterial endothelial cells (AEC) are recognized by CTL through class I antigens, as are PHA blasts; however, venous endothelial cells (VEC) appeared to be recognized through determinants not recognized on PHA blasts.

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JO - Transplantation Proceedings

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Cell-mediated cytotoxicity targets on canine endothelial cells

Abstract

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