TY - JOUR
T1 - Causes of infectious pediatric uveitis
T2 - A review
AU - Ngathaweesuk, Yaninsiri
AU - Hendrikse, Jytte
AU - Groot-Mijnes, Jolanda Dorothea Francisca de
AU - de Boer, Joke Helena
AU - Hettinga, Ymkje Marije
N1 - Publisher Copyright:
© 2024 The Authors
PY - 2024/5/1
Y1 - 2024/5/1
N2 - Infectious pediatric uveitis is a rare disease that can cause severe ocular damage if not detected rapidly and treated properly. Additionally, early identification of an infection can protect the child from life-threatening systemic infection. Infectious uveitis can be congenital or acquired and may manifest as a primary ocular infection or as a reactivation. Nevertheless, publications on infectious paediatric uveitis are usually limited to a small number of patients or a case report. So far, most studies on uveitis in children have focused primarily on noninfectious uveitis, and a systematic study on infectious uveitis is lacking. In this review, we summarize the literature on infectious uveitis in pediatric populations and report on the epidemiology, pathophysiology, clinical signs, diagnostic tests, and treatment. We will describe the different possible pathogens causing uveitis in childhood by microbiological group (i.e. parasites, viruses, bacteria, and fungi). We aim to contribute to early diagnosis and management of infectious pediatric uveitis, which in turn might improve not only visual outcome, but also the general health outcome.
AB - Infectious pediatric uveitis is a rare disease that can cause severe ocular damage if not detected rapidly and treated properly. Additionally, early identification of an infection can protect the child from life-threatening systemic infection. Infectious uveitis can be congenital or acquired and may manifest as a primary ocular infection or as a reactivation. Nevertheless, publications on infectious paediatric uveitis are usually limited to a small number of patients or a case report. So far, most studies on uveitis in children have focused primarily on noninfectious uveitis, and a systematic study on infectious uveitis is lacking. In this review, we summarize the literature on infectious uveitis in pediatric populations and report on the epidemiology, pathophysiology, clinical signs, diagnostic tests, and treatment. We will describe the different possible pathogens causing uveitis in childhood by microbiological group (i.e. parasites, viruses, bacteria, and fungi). We aim to contribute to early diagnosis and management of infectious pediatric uveitis, which in turn might improve not only visual outcome, but also the general health outcome.
KW - Bacteria
KW - Childhood uveitis
KW - Congenital infection
KW - Fungi
KW - Goldmann witmer coefficient
KW - Infectious uveitis
KW - Paediatric uveitis
KW - Parasite
KW - Polymerase chain reaction
KW - Serology
KW - Virus
UR - http://www.scopus.com/inward/record.url?scp=85184724270&partnerID=8YFLogxK
U2 - 10.1016/j.survophthal.2023.12.003
DO - 10.1016/j.survophthal.2023.12.003
M3 - Review article
C2 - 38182040
AN - SCOPUS:85184724270
SN - 0039-6257
VL - 69
SP - 483
EP - 494
JO - Survey of ophthalmology
JF - Survey of ophthalmology
IS - 3
ER -