Causes of infectious pediatric uveitis: A review

Yaninsiri Ngathaweesuk, Jytte Hendrikse*, Jolanda Dorothea Francisca de Groot-Mijnes, Joke Helena de Boer, Ymkje Marije Hettinga

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Infectious pediatric uveitis is a rare disease that can cause severe ocular damage if not detected rapidly and treated properly. Additionally, early identification of an infection can protect the child from life-threatening systemic infection. Infectious uveitis can be congenital or acquired and may manifest as a primary ocular infection or as a reactivation. Nevertheless, publications on infectious paediatric uveitis are usually limited to a small number of patients or a case report. So far, most studies on uveitis in children have focused primarily on noninfectious uveitis, and a systematic study on infectious uveitis is lacking. In this review, we summarize the literature on infectious uveitis in pediatric populations and report on the epidemiology, pathophysiology, clinical signs, diagnostic tests, and treatment. We will describe the different possible pathogens causing uveitis in childhood by microbiological group (i.e. parasites, viruses, bacteria, and fungi). We aim to contribute to early diagnosis and management of infectious pediatric uveitis, which in turn might improve not only visual outcome, but also the general health outcome.

Original languageEnglish
Pages (from-to)483-494
Number of pages12
JournalSurvey of ophthalmology
Volume69
Issue number3
DOIs
Publication statusPublished - 1 May 2024

Keywords

  • Bacteria
  • Childhood uveitis
  • Congenital infection
  • Fungi
  • Goldmann witmer coefficient
  • Infectious uveitis
  • Paediatric uveitis
  • Parasite
  • Polymerase chain reaction
  • Serology
  • Virus

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