Case series of three adult patients with exceptional clinical presentations of haemophagocytic lymphohistiocytosis

M. Khairoun; F. Meynen; W. Vercoutere; H. L. Leavis

Case series of three adult patients with exceptional clinical presentations of haemophagocytic lymphohistiocytosis

M. Khairoun
, F. Meynen
, W. Vercoutere
, H. L. Leavis^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Macrophage activation syndrome (MAS) is a secondary form of haemophagocytic lymphohistiocytosis (HLH). MAS-HLH is an underrecognised and life-threatening condition associated with a heterogeneous group of diseases including connective tissue disease and inflammatory disorders. Here, we report three cases of adult patients with MAS-HLH triggered by different entities, including systemic lupus erythematosus, Griscelli syndrome type 2, and Adult onset Still’s disease.

Original language	English
Pages (from-to)	136-141
Number of pages	6
Journal	Netherlands Journal of Medicine
Volume	78
Issue number	3
Publication status	Published - Apr 2020

Keywords

Adults still’s disease
Griscelli syndrome type 2
Haemo- phagocytic lymphohistiocytosis
Macrophage activation syndrome
Systemic lupus erythematosus

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title = "Case series of three adult patients with exceptional clinical presentations of haemophagocytic lymphohistiocytosis",

abstract = "Macrophage activation syndrome (MAS) is a secondary form of haemophagocytic lymphohistiocytosis (HLH). MAS-HLH is an underrecognised and life-threatening condition associated with a heterogeneous group of diseases including connective tissue disease and inflammatory disorders. Here, we report three cases of adult patients with MAS-HLH triggered by different entities, including systemic lupus erythematosus, Griscelli syndrome type 2, and Adult onset Still{\textquoteright}s disease.",

keywords = "Adults still{\textquoteright}s disease, Griscelli syndrome type 2, Haemo- phagocytic lymphohistiocytosis, Macrophage activation syndrome, Systemic lupus erythematosus",

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AU - Khairoun, M.

AU - Meynen, F.

AU - Vercoutere, W.

AU - Leavis, H. L.

PY - 2020/4

Y1 - 2020/4

N2 - Macrophage activation syndrome (MAS) is a secondary form of haemophagocytic lymphohistiocytosis (HLH). MAS-HLH is an underrecognised and life-threatening condition associated with a heterogeneous group of diseases including connective tissue disease and inflammatory disorders. Here, we report three cases of adult patients with MAS-HLH triggered by different entities, including systemic lupus erythematosus, Griscelli syndrome type 2, and Adult onset Still’s disease.

AB - Macrophage activation syndrome (MAS) is a secondary form of haemophagocytic lymphohistiocytosis (HLH). MAS-HLH is an underrecognised and life-threatening condition associated with a heterogeneous group of diseases including connective tissue disease and inflammatory disorders. Here, we report three cases of adult patients with MAS-HLH triggered by different entities, including systemic lupus erythematosus, Griscelli syndrome type 2, and Adult onset Still’s disease.

KW - Adults still’s disease

KW - Griscelli syndrome type 2

KW - Haemo- phagocytic lymphohistiocytosis

KW - Macrophage activation syndrome

KW - Systemic lupus erythematosus

UR - https://www.scopus.com/pages/publications/85084030392

M3 - Article

C2 - 32332189

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SN - 0300-2977

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SP - 136

EP - 141

JO - Netherlands Journal of Medicine

JF - Netherlands Journal of Medicine

IS - 3

ER -

Case series of three adult patients with exceptional clinical presentations of haemophagocytic lymphohistiocytosis

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Keywords

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