TY - JOUR
T1 - Case report
T2 - Coxiella burnetii vascular infection and lymphoma in the Netherlands
AU - van Roeden, Sonja E.
AU - Melenotte, Cléa
AU - Hermans, Mirjam H.A.
AU - Sinnige, Harm A M
AU - Nooijen, Peet T. G. A.
AU - Audoly, Gilles
AU - Hoepelman, Andy I.M.
AU - Oosterheert, Jan Jelrik
AU - Raoult, Didier
AU - Wever, Peter C.
N1 - Funding Information:
Acknowledgements This work was supported by Foundation Q-support [Grant number UMCU160707-00] and Institut Mérieux [Grant number UMCU17-3-01]. Both granted funding to the institution of S. E. van Roeden, J. J. Oosterheert and A. I. M. Hoepelman. The funding sources did not have any influence on design, performance or writing
Funding Information:
This work was supported by Foundation Q-support [Grant number UMCU160707-00] and Institut M?rieux [Grant number UMCU17-3-01]. Both granted funding to the institution of S. E. van Roeden, J. J. Oosterheert and A. I. M. Hoepelman. The funding sources did not have any influence on design, performance or writing of this scientific project and paper or decision to submit it to Infection. We thank the patient?s widow for granting us permission to publish this report. S. E. van Roeden: institution received research grant from foundation Q-support and Institut M?rieux, no other conflicts of interest. I confirm that we had full access to all data in the report and that we have final responsibility for the decision to submit this manuscript for the publication at Infection. No other conflicts of interest. C. Melenotte: no conflicts of interest. M. H. A. Hermans: no conflicts of interest. H. A. M. Sinnige: no conflicts of interest. P. T. G. A. Nooijen: no conflicts of interest. G. Audoly: no conflicts of interest. A. I. M. Hoepelman: institution received research grant from foundation Q-support and Institut M?rieux, no other conflicts of interest. J. J. Oosterheert: institution received research grant from foundation Q-support and Institut M?rieux, no other conflicts of interest. D. Raoult: no conflicts of interest. P. C. Wever: no conflicts of interest.
Publisher Copyright:
© 2017, The Author(s).
PY - 2018/2
Y1 - 2018/2
N2 - Objectives and design: Non-Hodgkin lymphoma has been linked to infection with Coxiella burnetii, potentially through overproduction of IL-10 during infection with C. burnetii. Materials and methods: Description of a case report. Results: We describe a patient with retroperitoneal non-Hodgkin lymphoma and vascular infection with C. burnetii. Immunofluorescence staining and fluorescence in situ hybridization targeting specific C. burnetii 16S rRNA were performed on the retroperitoneal lymphoma tissue sample obtained at diagnosis of NHL. Both were strongly positive for the presence of C. burnetii. Conclusions: This case provokes questions regarding a potential association between C. burnetii and NHL, and underlines the importance of further exploration of this association.
AB - Objectives and design: Non-Hodgkin lymphoma has been linked to infection with Coxiella burnetii, potentially through overproduction of IL-10 during infection with C. burnetii. Materials and methods: Description of a case report. Results: We describe a patient with retroperitoneal non-Hodgkin lymphoma and vascular infection with C. burnetii. Immunofluorescence staining and fluorescence in situ hybridization targeting specific C. burnetii 16S rRNA were performed on the retroperitoneal lymphoma tissue sample obtained at diagnosis of NHL. Both were strongly positive for the presence of C. burnetii. Conclusions: This case provokes questions regarding a potential association between C. burnetii and NHL, and underlines the importance of further exploration of this association.
KW - Coxiella burnetii
KW - Non-Hodgkin lymphoma
KW - Q fever
UR - http://www.scopus.com/inward/record.url?scp=85028349813&partnerID=8YFLogxK
U2 - 10.1007/s15010-017-1061-9
DO - 10.1007/s15010-017-1061-9
M3 - Article
C2 - 28840502
AN - SCOPUS:85028349813
SN - 0300-8126
VL - 46
SP - 131
EP - 134
JO - Infection
JF - Infection
IS - 1
ER -