Case 49: Theranostics for Brain Tumors

Nelleke Tolboom; Tom J. Snijders; Irene C. Van der Schaaf; Arthur J.A.T. Braat

doi:10.1007/978-3-032-00522-9_49

Case 49: Theranostics for Brain Tumors

Nelleke Tolboom^*
, Tom J. Snijders
, Irene C. Van der Schaaf
, Arthur J.A.T. Braat

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

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Abstract

Meningiomas are frequently encountered primary brain tumors. Surgery can be curative but there is risk for recurrence. In addition, certain tumor localizations can make surgery challenging or impossible. Radiotherapy is meaningful for certain cases, but still recurrences occur. Peptide receptor radionuclide therapy (PRRT) is a promising treatment for treatment refractory/ unresectable meningioma. An intra-arterial approach for administering PRRT to obtain high tumor dosages is feasible, without additional toxicity. Here we present a case of a patient with progressive recurrence of a meningioma, treated with intra-arterial PRRT.

Original language	English
Title of host publication	Coresource 4
Publisher	Springer Nature
Pages	241-245
Number of pages	5
ISBN (Electronic)	9783032005229
ISBN (Print)	9783032005212
DOIs	https://doi.org/10.1007/978-3-032-00522-9_49
Publication status	Published - 2025

Keywords

Intra-arterial
Meningiona
PRRT
Theranostic

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10.1007/978-3-032-00522-9_49

978-3-032-00522-9_49Final published version, 1.72 MBLicence: Taverne

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AU - Snijders, Tom J.

AU - Van der Schaaf, Irene C.

AU - Braat, Arthur J.A.T.

N1 - Publisher Copyright: © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.

PY - 2025

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N2 - Meningiomas are frequently encountered primary brain tumors. Surgery can be curative but there is risk for recurrence. In addition, certain tumor localizations can make surgery challenging or impossible. Radiotherapy is meaningful for certain cases, but still recurrences occur. Peptide receptor radionuclide therapy (PRRT) is a promising treatment for treatment refractory/ unresectable meningioma. An intra-arterial approach for administering PRRT to obtain high tumor dosages is feasible, without additional toxicity. Here we present a case of a patient with progressive recurrence of a meningioma, treated with intra-arterial PRRT.

AB - Meningiomas are frequently encountered primary brain tumors. Surgery can be curative but there is risk for recurrence. In addition, certain tumor localizations can make surgery challenging or impossible. Radiotherapy is meaningful for certain cases, but still recurrences occur. Peptide receptor radionuclide therapy (PRRT) is a promising treatment for treatment refractory/ unresectable meningioma. An intra-arterial approach for administering PRRT to obtain high tumor dosages is feasible, without additional toxicity. Here we present a case of a patient with progressive recurrence of a meningioma, treated with intra-arterial PRRT.

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KW - PRRT

KW - Theranostic

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ER -

Case 49: Theranostics for Brain Tumors

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