Cardiac CT in CRT as a Singular Imaging Modality for Diagnosis and Patient-Tailored Management

Willem Gerrits*, Ibrahim Danad, Birgitta Velthuis, Saima Mushtaq, Maarten J. Cramer, Pim van der Harst, Frebus J. van Slochteren, Mathias Meine, Dominika Suchá, Marco Guglielmo

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

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Abstract

Between 30–40% of patients with cardiac resynchronization therapy (CRT) do not show an improvement in left ventricular (LV) function. It is generally known that patient selection, LV lead implantation location, and device timing optimization are the three main factors that determine CRT response. Research has shown that image-guided CRT placement, which takes into account both anatomical and functional cardiac properties, positively affects the CRT response rate. In current clinical practice, a multimodality imaging approach comprised of echocardiography, cardiac magnetic resonance imaging, or nuclear medicine imaging is used to capture these features. However, with cardiac computed tomography (CT), one has an all-in-one acquisition method for both patient selection and the division of a patient-tailored, image-guided CRT placement strategy. This review discusses the applicability of CT in CRT patient identification, selection, and guided placement, offering insights into potential advancements in optimizing CRT outcomes.

Original languageEnglish
Article number6212
JournalJournal of Clinical medicine
Volume12
Issue number19
DOIs
Publication statusPublished - Oct 2023

Keywords

  • cardiac resynchronization therapy
  • computed tomography
  • heart failure

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