TY - JOUR
T1 - Cardiac care of non-covid-19 patients during the sars-cov-2 pandemic
T2 - The pivotal role of ccta
AU - Conte, Edoardo
AU - Mushtaq, Saima
AU - Mancini, Maria Elisabetta
AU - Annoni, Andrea
AU - Formenti, Alberto
AU - Muscogiuri, Giuseppe
AU - Asinelli, Margherita Gaudenzi
AU - Gigante, Carlo
AU - Collet, Carlos
AU - Sonck, Jeroen
AU - Guglielmo, Marco
AU - Baggiano, Andrea
AU - Cosentino, Nicola
AU - Denora, Marialessia
AU - Belmonte, Marta
AU - Agalbato, Cecilia
AU - Esposito, Andrea Alessandro
AU - Assanelli, Emilio
AU - Bartorelli, Antonio L.
AU - Pepi, Mauro
AU - Pontone, Gianluca
AU - Andreini, Daniele
N1 - Publisher Copyright:
© 2021 Conte, Mushtaq, Mancini, Annoni, Formenti, Muscogiuri, Gaudenzi Asinelli, Gigante, Collet, Sonck, Guglielmo, Baggiano, Cosentino, Denora, Belmonte, Agalbato, Esposito, Assanelli, Bartorelli, Pepi, Pontone and Andreini.
PY - 2021
Y1 - 2021
N2 - Aim: The aim of this study is to evaluate the potential use of coronary CT angiography (CCTA) as the sole available non-invasive diagnostic technique for suspected coronary artery disease (CAD) during the coronavirus disease 2019 (COVID-19) pandemic causing limited access to the hospital facilities. Methods and Results: A consecutive cohort of patients with suspected stable CAD and clinical indication to non-invasive test was enrolled in a hub hospital in Milan, Italy, from March 9 to April 30, 2020. Outcome measures were obtained as follows: cardiac death, ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI), and unstable angina. All the changes in medical therapy following the result of CCTA were annotated. A total of 58 patients with a mean age of 64 ± 11 years (36 men and 22 women) were enrolled. CCTA showed no CAD in 14 patients (24.1%), non-obstructive CAD in 30 (51.7%) patients, and obstructive CAD in 14 (24.1%) patients. Invasive coronary angiography (ICA) was considered deferrable in 48 (82.8%) patients. No clinical events were recorded after a mean follow-up of 376.4 ± 32.1 days. Changes in the medical therapy were significantly more prevalent in patients with vs. those without CAD at CCTA. Conclusion: The results of the study confirm the capability of CCTA to safely defer ICA in the majority of symptomatic patients and to correctly identify those with critical coronary stenoses necessitating coronary revascularization.
AB - Aim: The aim of this study is to evaluate the potential use of coronary CT angiography (CCTA) as the sole available non-invasive diagnostic technique for suspected coronary artery disease (CAD) during the coronavirus disease 2019 (COVID-19) pandemic causing limited access to the hospital facilities. Methods and Results: A consecutive cohort of patients with suspected stable CAD and clinical indication to non-invasive test was enrolled in a hub hospital in Milan, Italy, from March 9 to April 30, 2020. Outcome measures were obtained as follows: cardiac death, ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI), and unstable angina. All the changes in medical therapy following the result of CCTA were annotated. A total of 58 patients with a mean age of 64 ± 11 years (36 men and 22 women) were enrolled. CCTA showed no CAD in 14 patients (24.1%), non-obstructive CAD in 30 (51.7%) patients, and obstructive CAD in 14 (24.1%) patients. Invasive coronary angiography (ICA) was considered deferrable in 48 (82.8%) patients. No clinical events were recorded after a mean follow-up of 376.4 ± 32.1 days. Changes in the medical therapy were significantly more prevalent in patients with vs. those without CAD at CCTA. Conclusion: The results of the study confirm the capability of CCTA to safely defer ICA in the majority of symptomatic patients and to correctly identify those with critical coronary stenoses necessitating coronary revascularization.
KW - Atherosclerosis
KW - Cardiac CT
KW - Chest pain
KW - Coronary artery disease
KW - COVID-19
UR - http://www.scopus.com/inward/record.url?scp=85122829465&partnerID=8YFLogxK
U2 - 10.3389/fcvm.2021.775115
DO - 10.3389/fcvm.2021.775115
M3 - Article
AN - SCOPUS:85122829465
SN - 2297-055X
VL - 8
JO - Frontiers in Cardiovascular Medicine
JF - Frontiers in Cardiovascular Medicine
M1 - 775115
ER -