C-reactive protein point-of-care testing in children with cough: Qualitative study of GPs' perceptions

Marjolein J.C. Schot*, Berna D.L. Broekhuizen, Jochen W.L. Cals, Esther Brussee, Niek J. de Wit, Theo J.M. Verheij, Esther de Groot

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)


Background: Point-of-care C-reactive protein (CRP) testing is widely accepted in Dutch general practice for adult patients with acute cough, but GPs' perceptions of its use in children with suspected lower respiratory tract infection (LRTI) are unknown. Knowledge of these perceptions is important when considering broadening its indication to use in children. Aim: To explore the perceptions of Dutch GPs of the addition of point-of-care CRP testing to the diagnostic evaluation of children, and compare these to their perceptions of use in adults. Design & setting: A qualitative study in general practice in the Netherlands. Method: Semi-structured interviews were held with 11 GPs. Interviews were analysed using open coding and a thematic approach. Results: GPs' perceptions of the addition of point-of-care CRP testing to diagnostic process in children with suspected LRTI differ from their perceptions of this in adults. Five themes were identified: patient characteristics; vulnerability of the child; clinical presentation; availability of evidence; the impact of the procedure; and use of point-of-care CRP testing as a communication tool. Conclusion: Differences between the perceptions of using point-of-care CRP testing in children and adults need to be addressed when considering the possible implementation of this diagnostic instrument.

Original languageEnglish
Article numberbjgpopen17X101193
JournalBJGP Open
Issue number4
Publication statusPublished - 1 Jan 2018


  • C-reactive protein
  • Child
  • Point-of-care testing
  • Primary health care
  • Qualitative research
  • Respiratory tract infections


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