Bridging Science and Hope: integrating and Communicating Lived experience in Accelerating Medicines Partnership® Schizophrenia Program

Ameneh Asgari-Targhi; Beier Yao; Lisa Brown; Suzanne Garcia; Arundati Nagendra; Kota Chin; Tashrif Billah; Nora Penzel; Omar John; Nicholas Prunier; Simone Veale; Elana Kotler; Grace R Jacobs; Ming Zhan; Michael J Coleman; Sylvain Bouix; Ofer Pasternak; Guillermo Cecci; Justin T Baker; Daniel H Mathalon; Sinead M Kelly; Cheryl M Corcoran; Abraham Reichenberg; Inge Winter-van Rossum; Marek Kubicki; Jessica Spark; Dominic Dwyer; Celso Arango; Paolo Fusar-Poli; Monica Calkins; Jai L Shah; Vijay Mittal; Andrew Thompson; Patrick D McGorry; René S Kahn; John M Kane; Carrie E Bearden; Scott W Woods; Barnaby Nelson; Martha E Shenton; Brandon Staglin; Carlos A Larrauri; Kathryn Eve Lewandowski; Tina Kapur

doi:10.1038/s41537-025-00572-7

Bridging Science and Hope: integrating and Communicating Lived experience in Accelerating Medicines Partnership® Schizophrenia Program

Ameneh Asgari-Targhi, Beier Yao, Lisa Brown, Suzanne Garcia, Arundati Nagendra, Kota Chin, Tashrif Billah, Nora Penzel, Omar John, Nicholas Prunier, Simone Veale, Elana Kotler, Grace R Jacobs, Ming Zhan, Michael J Coleman, Sylvain Bouix, Ofer Pasternak, Guillermo Cecci, Justin T Baker, Daniel H MathalonSinead M Kelly, Cheryl M Corcoran, Abraham Reichenberg, Inge Winter-van Rossum, Marek Kubicki, Jessica Spark, Dominic Dwyer, Celso Arango, Paolo Fusar-Poli, Monica Calkins, Jai L Shah, Vijay Mittal, Andrew Thompson, Patrick D McGorry, René S Kahn, John M Kane, Carrie E Bearden, Scott W Woods, Barnaby Nelson, Martha E Shenton, Brandon Staglin, Carlos A Larrauri, Kathryn Eve Lewandowski, Tina Kapur^*,

^*Corresponding author for this work

Research output: Contribution to journal › Letter › Academic › peer-review

Abstract

The Accelerating Medicines Partnership Schizophrenia (AMP® SCZ) program integrates lived experience into psychosis research, leveraging over three decades of foundational studies to improve research quality, promote community engagement, and ensure ethical implementation of precision psychiatry. Lived experience is embedded in the program’s governance, shaping study protocols, recruitment strategies, and digital tools such as the mindLAMP platform. Study sites also integrate lived experience through youth advisory boards, peer support specialists, and advisory committees, ensuring diverse perspectives inform research design and implementation. These efforts aim to develop predictive tools and therapeutic strategies while maintaining ethical and participant-centered practices. Advocacy organizations, such as the National Alliance on Mental Illness (NAMI), have fostered collaboration among government, industry, and academic partners, shaping outreach and engagement strategies. Dissemination efforts, led by the Website and Outreach Workgroup (WOW), include an accessible, Section 508-compliant website and co-designed resources, building trust and engagement within communities. By integrating lived experience at every stage, the program aims to foster trust, enhance research outcomes, and inform future strategies for treatment and prevention. Watch Dr. Tina Kapur, Dr. Kathryn Eve Lewandowski, and Dr. Carlos A. Larrauri discuss this article and their work at: https://vimeo.com/1050068801.

Original language	English
Article number	57
Journal	Schizophrenia
Volume	11
Issue number	1
DOIs	https://doi.org/10.1038/s41537-025-00572-7
Publication status	Published - 7 Apr 2025
Externally published	Yes

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Asgari-Targhi, A., Yao, B., Brown, L., Garcia, S., Nagendra, A., Chin, K., Billah, T., Penzel, N., John, O., Prunier, N., Veale, S., Kotler, E., Jacobs, G. R., Zhan, M., Coleman, M. J., Bouix, S., Pasternak, O., Cecci, G., Baker, J. T. (2025). Bridging Science and Hope: integrating and Communicating Lived experience in Accelerating Medicines Partnership® Schizophrenia Program. Schizophrenia, 11(1), Article 57. https://doi.org/10.1038/s41537-025-00572-7

@article{21c8bffb31984116b5b784ac185a12b7,

title = "Bridging Science and Hope: integrating and Communicating Lived experience in Accelerating Medicines Partnership{\textregistered} Schizophrenia Program",

abstract = "The Accelerating Medicines Partnership Schizophrenia (AMP{\textregistered} SCZ) program integrates lived experience into psychosis research, leveraging over three decades of foundational studies to improve research quality, promote community engagement, and ensure ethical implementation of precision psychiatry. Lived experience is embedded in the program{\textquoteright}s governance, shaping study protocols, recruitment strategies, and digital tools such as the mindLAMP platform. Study sites also integrate lived experience through youth advisory boards, peer support specialists, and advisory committees, ensuring diverse perspectives inform research design and implementation. These efforts aim to develop predictive tools and therapeutic strategies while maintaining ethical and participant-centered practices. Advocacy organizations, such as the National Alliance on Mental Illness (NAMI), have fostered collaboration among government, industry, and academic partners, shaping outreach and engagement strategies. Dissemination efforts, led by the Website and Outreach Workgroup (WOW), include an accessible, Section 508-compliant website and co-designed resources, building trust and engagement within communities. By integrating lived experience at every stage, the program aims to foster trust, enhance research outcomes, and inform future strategies for treatment and prevention. Watch Dr. Tina Kapur, Dr. Kathryn Eve Lewandowski, and Dr. Carlos A. Larrauri discuss this article and their work at: https://vimeo.com/1050068801.",

author = "Ameneh Asgari-Targhi and Beier Yao and Lisa Brown and Suzanne Garcia and Arundati Nagendra and Kota Chin and Tashrif Billah and Nora Penzel and Omar John and Nicholas Prunier and Simone Veale and Elana Kotler and Jacobs, {Grace R} and Ming Zhan and Coleman, {Michael J} and Sylvain Bouix and Ofer Pasternak and Guillermo Cecci and Baker, {Justin T} and Mathalon, {Daniel H} and Kelly, {Sinead M} and Corcoran, {Cheryl M} and Abraham Reichenberg and {Winter-van Rossum}, Inge and Marek Kubicki and Jessica Spark and Dominic Dwyer and Celso Arango and Paolo Fusar-Poli and Monica Calkins and Shah, {Jai L} and Vijay Mittal and Andrew Thompson and McGorry, {Patrick D} and Kahn, {Ren{\'e} S} and Kane, {John M} and Bearden, {Carrie E} and Woods, {Scott W} and Barnaby Nelson and Shenton, {Martha E} and Brandon Staglin and Larrauri, {Carlos A} and Lewandowski, {Kathryn Eve} and Tina Kapur",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2025.",

year = "2025",

month = apr,

day = "7",

doi = "10.1038/s41537-025-00572-7",

language = "English",

volume = "11",

journal = "Schizophrenia",

issn = "2754-6993",

number = "1",

}

Asgari-Targhi, A, Yao, B, Brown, L, Garcia, S, Nagendra, A, Chin, K, Billah, T, Penzel, N, John, O, Prunier, N, Veale, S, Kotler, E, Jacobs, GR, Zhan, M, Coleman, MJ, Bouix, S, Pasternak, O, Cecci, G, Baker, JT, Mathalon, DH, Kelly, SM, Corcoran, CM, Reichenberg, A, Winter-van Rossum, I, Kubicki, M, Spark, J, Dwyer, D, Arango, C, Fusar-Poli, P, Calkins, M, Shah, JL, Mittal, V, Thompson, A, McGorry, PD, Kahn, RS, Kane, JM, Bearden, CE, Woods, SW, Nelson, B, Shenton, ME, Staglin, B, Larrauri, CA, Lewandowski, KE, Kapur, T 2025, 'Bridging Science and Hope: integrating and Communicating Lived experience in Accelerating Medicines Partnership® Schizophrenia Program', Schizophrenia, vol. 11, no. 1, 57. https://doi.org/10.1038/s41537-025-00572-7

TY - JOUR

T1 - Bridging Science and Hope

T2 - integrating and Communicating Lived experience in Accelerating Medicines Partnership® Schizophrenia Program

AU - Asgari-Targhi, Ameneh

AU - Yao, Beier

AU - Brown, Lisa

AU - Garcia, Suzanne

AU - Nagendra, Arundati

AU - Chin, Kota

AU - Billah, Tashrif

AU - Penzel, Nora

AU - John, Omar

AU - Prunier, Nicholas

AU - Veale, Simone

AU - Kotler, Elana

AU - Jacobs, Grace R

AU - Zhan, Ming

AU - Coleman, Michael J

AU - Bouix, Sylvain

AU - Pasternak, Ofer

AU - Cecci, Guillermo

AU - Baker, Justin T

AU - Mathalon, Daniel H

AU - Kelly, Sinead M

AU - Corcoran, Cheryl M

AU - Reichenberg, Abraham

AU - Winter-van Rossum, Inge

AU - Kubicki, Marek

AU - Spark, Jessica

AU - Dwyer, Dominic

AU - Arango, Celso

AU - Fusar-Poli, Paolo

AU - Calkins, Monica

AU - Shah, Jai L

AU - Mittal, Vijay

AU - Thompson, Andrew

AU - McGorry, Patrick D

AU - Kahn, René S

AU - Kane, John M

AU - Bearden, Carrie E

AU - Woods, Scott W

AU - Nelson, Barnaby

AU - Shenton, Martha E

AU - Staglin, Brandon

AU - Larrauri, Carlos A

AU - Lewandowski, Kathryn Eve

AU - Kapur, Tina

PY - 2025/4/7

Y1 - 2025/4/7

N2 - The Accelerating Medicines Partnership Schizophrenia (AMP® SCZ) program integrates lived experience into psychosis research, leveraging over three decades of foundational studies to improve research quality, promote community engagement, and ensure ethical implementation of precision psychiatry. Lived experience is embedded in the program’s governance, shaping study protocols, recruitment strategies, and digital tools such as the mindLAMP platform. Study sites also integrate lived experience through youth advisory boards, peer support specialists, and advisory committees, ensuring diverse perspectives inform research design and implementation. These efforts aim to develop predictive tools and therapeutic strategies while maintaining ethical and participant-centered practices. Advocacy organizations, such as the National Alliance on Mental Illness (NAMI), have fostered collaboration among government, industry, and academic partners, shaping outreach and engagement strategies. Dissemination efforts, led by the Website and Outreach Workgroup (WOW), include an accessible, Section 508-compliant website and co-designed resources, building trust and engagement within communities. By integrating lived experience at every stage, the program aims to foster trust, enhance research outcomes, and inform future strategies for treatment and prevention. Watch Dr. Tina Kapur, Dr. Kathryn Eve Lewandowski, and Dr. Carlos A. Larrauri discuss this article and their work at: https://vimeo.com/1050068801.

AB - The Accelerating Medicines Partnership Schizophrenia (AMP® SCZ) program integrates lived experience into psychosis research, leveraging over three decades of foundational studies to improve research quality, promote community engagement, and ensure ethical implementation of precision psychiatry. Lived experience is embedded in the program’s governance, shaping study protocols, recruitment strategies, and digital tools such as the mindLAMP platform. Study sites also integrate lived experience through youth advisory boards, peer support specialists, and advisory committees, ensuring diverse perspectives inform research design and implementation. These efforts aim to develop predictive tools and therapeutic strategies while maintaining ethical and participant-centered practices. Advocacy organizations, such as the National Alliance on Mental Illness (NAMI), have fostered collaboration among government, industry, and academic partners, shaping outreach and engagement strategies. Dissemination efforts, led by the Website and Outreach Workgroup (WOW), include an accessible, Section 508-compliant website and co-designed resources, building trust and engagement within communities. By integrating lived experience at every stage, the program aims to foster trust, enhance research outcomes, and inform future strategies for treatment and prevention. Watch Dr. Tina Kapur, Dr. Kathryn Eve Lewandowski, and Dr. Carlos A. Larrauri discuss this article and their work at: https://vimeo.com/1050068801.

U2 - 10.1038/s41537-025-00572-7

DO - 10.1038/s41537-025-00572-7

M3 - Letter

C2 - 40195300

SN - 2754-6993

VL - 11

JO - Schizophrenia

JF - Schizophrenia

IS - 1

M1 - 57

ER -

Bridging Science and Hope: integrating and Communicating Lived experience in Accelerating Medicines Partnership® Schizophrenia Program

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