TY - JOUR
T1 - Breathing variability-implications for anaesthesiology and intensive care
AU - van den Bosch, Oscar F C
AU - Alvarez-Jimenez, Ricardo
AU - de Grooth, Harm-Jan
AU - Girbes, Armand R J
AU - Loer, Stephan A
N1 - Publisher Copyright:
© 2021, The Author(s).
PY - 2021/12
Y1 - 2021/12
N2 - The respiratory system reacts instantaneously to intrinsic and extrinsic inputs. This adaptability results in significant fluctuations in breathing parameters, such as respiratory rate, tidal volume, and inspiratory flow profiles. Breathing variability is influenced by several conditions, including sleep, various pulmonary diseases, hypoxia, and anxiety disorders. Recent studies have suggested that weaning failure during mechanical ventilation may be predicted by low respiratory variability. This review describes methods for quantifying breathing variability, summarises the conditions and comorbidities that affect breathing variability, and discusses the potential implications of breathing variability for anaesthesia and intensive care.
AB - The respiratory system reacts instantaneously to intrinsic and extrinsic inputs. This adaptability results in significant fluctuations in breathing parameters, such as respiratory rate, tidal volume, and inspiratory flow profiles. Breathing variability is influenced by several conditions, including sleep, various pulmonary diseases, hypoxia, and anxiety disorders. Recent studies have suggested that weaning failure during mechanical ventilation may be predicted by low respiratory variability. This review describes methods for quantifying breathing variability, summarises the conditions and comorbidities that affect breathing variability, and discusses the potential implications of breathing variability for anaesthesia and intensive care.
KW - Coefficient of variation
KW - Control of breathing
KW - Detrended fluctuation analysis
KW - Entropy analysis
KW - Perioperative period
KW - Respiratory variability
KW - Spontaneous breathing trial
KW - Spontaneous respiration
UR - http://www.scopus.com/inward/record.url?scp=85111974770&partnerID=8YFLogxK
U2 - 10.1186/s13054-021-03716-0
DO - 10.1186/s13054-021-03716-0
M3 - Review article
C2 - 34353348
SN - 1466-609X
VL - 25
SP - 280
JO - Critical care (London, England)
JF - Critical care (London, England)
IS - 1
M1 - 280
ER -