Abstract
Fluoxetine (Prozac) and fluvoxamine (Fevarin) are nontricyclic serotonin (5-hydroxytryptamine) reuptake inhibitors prescribed for the treatment of depression. Since these drugs block serotonin reuptake in platelets also, they might under certain conditions lead to clinically significant platelet dysfunction. Four patients are described who developed bleeding during treatment with either fluoxetine or fluvoxamine.
| Translated title of the contribution | Risk of hemorrhage with the use of fluoxetine (Prozac) or fluvoxamine (Fevarin) |
|---|---|
| Original language | Dutch |
| Pages (from-to) | 259-61 |
| Number of pages | 3 |
| Journal | Nederlands Tijdschrift voor Geneeskunde |
| Volume | 137 |
| Issue number | 5 |
| Publication status | Published - 30 Jan 1993 |
| Externally published | Yes |
Keywords
- Adult
- Female
- Fluoxetine/adverse effects
- Fluvoxamine/adverse effects
- Hematoma/chemically induced
- Hemorrhage/chemically induced
- Humans
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