Birth and upgrowth of the Hox topological domains during evolution

J. Deschamps

doi:10.1038/ng.3514

Birth and upgrowth of the Hox topological domains during evolution

J. Deschamps^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The recently discovered chromatin compartments called topologically associating domains (TADs) are essential for the three-dimensional organization of regulatory interactions driving gene expression. A new study documents the emergence of a TAD flanking the amphioxus Hox cluster, prefiguring the vertebrate anterior Hox TAD and preceding the appearance of the concurring posterior Hox TAD.

Original language	English
Pages (from-to)	227-228
Number of pages	2
Journal	Nature Genetics
Volume	48
Issue number	3
DOIs	https://doi.org/10.1038/ng.3514
Publication status	Published - 1 Mar 2016

Access to Document

10.1038/ng.3514

Cite this

@article{9ecbfc0e4f964c178cc99586e89cf2fd,

title = "Birth and upgrowth of the Hox topological domains during evolution",

abstract = "The recently discovered chromatin compartments called topologically associating domains (TADs) are essential for the three-dimensional organization of regulatory interactions driving gene expression. A new study documents the emergence of a TAD flanking the amphioxus Hox cluster, prefiguring the vertebrate anterior Hox TAD and preceding the appearance of the concurring posterior Hox TAD.",

author = "J. Deschamps",

year = "2016",

month = mar,

day = "1",

doi = "10.1038/ng.3514",

language = "English",

volume = "48",

pages = "227--228",

journal = "Nature Genetics",

issn = "1061-4036",

publisher = "Nature Research",

number = "3",

}

TY - JOUR

T1 - Birth and upgrowth of the Hox topological domains during evolution

AU - Deschamps, J.

PY - 2016/3/1

Y1 - 2016/3/1

N2 - The recently discovered chromatin compartments called topologically associating domains (TADs) are essential for the three-dimensional organization of regulatory interactions driving gene expression. A new study documents the emergence of a TAD flanking the amphioxus Hox cluster, prefiguring the vertebrate anterior Hox TAD and preceding the appearance of the concurring posterior Hox TAD.

AB - The recently discovered chromatin compartments called topologically associating domains (TADs) are essential for the three-dimensional organization of regulatory interactions driving gene expression. A new study documents the emergence of a TAD flanking the amphioxus Hox cluster, prefiguring the vertebrate anterior Hox TAD and preceding the appearance of the concurring posterior Hox TAD.

UR - https://www.scopus.com/pages/publications/84959350589

U2 - 10.1038/ng.3514

DO - 10.1038/ng.3514

M3 - Article

C2 - 26906681

AN - SCOPUS:84959350589

SN - 1061-4036

VL - 48

SP - 227

EP - 228

JO - Nature Genetics

JF - Nature Genetics

IS - 3

ER -

Birth and upgrowth of the Hox topological domains during evolution

Abstract

Access to Document

Other files and links

Fingerprint

Cite this