Birth and upgrowth of the Hox topological domains during evolution

J. Deschamps*

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    Abstract

    The recently discovered chromatin compartments called topologically associating domains (TADs) are essential for the three-dimensional organization of regulatory interactions driving gene expression. A new study documents the emergence of a TAD flanking the amphioxus Hox cluster, prefiguring the vertebrate anterior Hox TAD and preceding the appearance of the concurring posterior Hox TAD.

    Original languageEnglish
    Pages (from-to)227-228
    Number of pages2
    JournalNature Genetics
    Volume48
    Issue number3
    DOIs
    Publication statusPublished - 1 Mar 2016

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