BiomarCaRE: rationale and design of the European BiomarCaRE project including 300,000 participants from 13 European countries

Tanja Zeller; Maria Hughes; Tarja Tuovinen; Arne Schillert; Annette Conrads-Frank; Hester den Ruijter; Renate B. Schnabel; Frank Kee; Veikko Salomaa; Uwe Siebert; Barbara Thorand; Andreas Ziegler; Heico Breek; Gerard Pasterkamp; Kari Kuulasmaa; Wolfgang Koenig; Stefan Blankenberg

doi:10.1007/s10654-014-9952-x.

BiomarCaRE: rationale and design of the European BiomarCaRE project including 300,000 participants from 13 European countries

Tanja Zeller^*, Maria Hughes, Tarja Tuovinen, Arne Schillert, Annette Conrads-Frank, Hester den Ruijter, Renate B. Schnabel, Frank Kee, Veikko Salomaa, Uwe Siebert, Barbara Thorand, Andreas Ziegler, Heico Breek, Gerard Pasterkamp, Kari Kuulasmaa, Wolfgang Koenig, Stefan Blankenberg

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Biomarkers are considered as tools to enhance cardiovascular risk estimation. However, the value of biomarkers on risk estimation beyond European risk scores, their comparative impact among different European regions and their role towards personalised medicine remains uncertain. Biomarker for Cardiovascular Risk Assessment in Europe (BiomarCaRE) is an European collaborative research project with the primary objective to assess the value of established and emerging biomarkers for cardiovascular risk prediction. BiomarCaRE integrates clinical and epidemiological biomarker research and commercial enterprises throughout Europe to combine innovation in biomarker discovery for cardiovascular disease prediction with consecutive validation of biomarker effectiveness in large, well-defined primary and secondary prevention cohorts including over 300,000 participants from 13 European countries. Results from this study will contribute to improved cardiovascular risk prediction across different European populations. The present publication describes the rationale and design of the BiomarCaRE project.

Original language	English
Pages (from-to)	777-790
Number of pages	14
Journal	European Journal of Epidemiology
Volume	29
Issue number	10
DOIs	https://doi.org/10.1007/s10654-014-9952-x. https://doi.org/10.1007/s10654-014-9952-x
Publication status	Published - Oct 2014

Keywords

BiomarCaRE
Biomarker
Cardiovascular Risk Assessment
MORGAM
EU
CORONARY-ARTERY-DISEASE
CARDIOVASCULAR-DISEASE
MYOCARDIAL-INFARCTION
VASCULAR EVENTS
RISK
BIOMARKERS
PREDICTION
PROTEIN
PROGNOSIS
DISCOVERY

Access to Document

http://link.springer.com/article/10.1007%2Fs10654-014-9952-x

Cite this

Zeller, T., Hughes, M., Tuovinen, T., Schillert, A., Conrads-Frank, A., den Ruijter, H., Schnabel, R. B., Kee, F., Salomaa, V., Siebert, U., Thorand, B., Ziegler, A., Breek, H., Pasterkamp, G., Kuulasmaa, K., Koenig, W., & Blankenberg, S. (2014). BiomarCaRE: rationale and design of the European BiomarCaRE project including 300,000 participants from 13 European countries. European Journal of Epidemiology, 29(10), 777-790. https://doi.org/10.1007/s10654-014-9952-x., https://doi.org/10.1007/s10654-014-9952-x

@article{e344a992a2174aa9958a39eb1701311a,

title = "BiomarCaRE: rationale and design of the European BiomarCaRE project including 300,000 participants from 13 European countries",

abstract = "Biomarkers are considered as tools to enhance cardiovascular risk estimation. However, the value of biomarkers on risk estimation beyond European risk scores, their comparative impact among different European regions and their role towards personalised medicine remains uncertain. Biomarker for Cardiovascular Risk Assessment in Europe (BiomarCaRE) is an European collaborative research project with the primary objective to assess the value of established and emerging biomarkers for cardiovascular risk prediction. BiomarCaRE integrates clinical and epidemiological biomarker research and commercial enterprises throughout Europe to combine innovation in biomarker discovery for cardiovascular disease prediction with consecutive validation of biomarker effectiveness in large, well-defined primary and secondary prevention cohorts including over 300,000 participants from 13 European countries. Results from this study will contribute to improved cardiovascular risk prediction across different European populations. The present publication describes the rationale and design of the BiomarCaRE project.",

keywords = "BiomarCaRE, Biomarker, Cardiovascular Risk Assessment, MORGAM, EU, CORONARY-ARTERY-DISEASE, CARDIOVASCULAR-DISEASE, MYOCARDIAL-INFARCTION, VASCULAR EVENTS, RISK, BIOMARKERS, PREDICTION, PROTEIN, PROGNOSIS, DISCOVERY",

author = "Tanja Zeller and Maria Hughes and Tarja Tuovinen and Arne Schillert and Annette Conrads-Frank and {den Ruijter}, Hester and Schnabel, {Renate B.} and Frank Kee and Veikko Salomaa and Uwe Siebert and Barbara Thorand and Andreas Ziegler and Heico Breek and Gerard Pasterkamp and Kari Kuulasmaa and Wolfgang Koenig and Stefan Blankenberg",

year = "2014",

month = oct,

doi = "10.1007/s10654-014-9952-x.",

language = "English",

volume = "29",

pages = "777--790",

journal = "European Journal of Epidemiology",

issn = "0393-2990",

publisher = "Springer Netherlands",

number = "10",

}

Zeller, T, Hughes, M, Tuovinen, T, Schillert, A, Conrads-Frank, A, den Ruijter, H, Schnabel, RB, Kee, F, Salomaa, V, Siebert, U, Thorand, B, Ziegler, A, Breek, H, Pasterkamp, G, Kuulasmaa, K, Koenig, W & Blankenberg, S 2014, 'BiomarCaRE: rationale and design of the European BiomarCaRE project including 300,000 participants from 13 European countries', European Journal of Epidemiology, vol. 29, no. 10, pp. 777-790. https://doi.org/10.1007/s10654-014-9952-x., https://doi.org/10.1007/s10654-014-9952-x

TY - JOUR

T1 - BiomarCaRE

T2 - rationale and design of the European BiomarCaRE project including 300,000 participants from 13 European countries

AU - Zeller, Tanja

AU - Hughes, Maria

AU - Tuovinen, Tarja

AU - Schillert, Arne

AU - Conrads-Frank, Annette

AU - den Ruijter, Hester

AU - Schnabel, Renate B.

AU - Kee, Frank

AU - Salomaa, Veikko

AU - Siebert, Uwe

AU - Thorand, Barbara

AU - Ziegler, Andreas

AU - Breek, Heico

AU - Pasterkamp, Gerard

AU - Kuulasmaa, Kari

AU - Koenig, Wolfgang

AU - Blankenberg, Stefan

PY - 2014/10

Y1 - 2014/10

N2 - Biomarkers are considered as tools to enhance cardiovascular risk estimation. However, the value of biomarkers on risk estimation beyond European risk scores, their comparative impact among different European regions and their role towards personalised medicine remains uncertain. Biomarker for Cardiovascular Risk Assessment in Europe (BiomarCaRE) is an European collaborative research project with the primary objective to assess the value of established and emerging biomarkers for cardiovascular risk prediction. BiomarCaRE integrates clinical and epidemiological biomarker research and commercial enterprises throughout Europe to combine innovation in biomarker discovery for cardiovascular disease prediction with consecutive validation of biomarker effectiveness in large, well-defined primary and secondary prevention cohorts including over 300,000 participants from 13 European countries. Results from this study will contribute to improved cardiovascular risk prediction across different European populations. The present publication describes the rationale and design of the BiomarCaRE project.

AB - Biomarkers are considered as tools to enhance cardiovascular risk estimation. However, the value of biomarkers on risk estimation beyond European risk scores, their comparative impact among different European regions and their role towards personalised medicine remains uncertain. Biomarker for Cardiovascular Risk Assessment in Europe (BiomarCaRE) is an European collaborative research project with the primary objective to assess the value of established and emerging biomarkers for cardiovascular risk prediction. BiomarCaRE integrates clinical and epidemiological biomarker research and commercial enterprises throughout Europe to combine innovation in biomarker discovery for cardiovascular disease prediction with consecutive validation of biomarker effectiveness in large, well-defined primary and secondary prevention cohorts including over 300,000 participants from 13 European countries. Results from this study will contribute to improved cardiovascular risk prediction across different European populations. The present publication describes the rationale and design of the BiomarCaRE project.

KW - BiomarCaRE

KW - Biomarker

KW - Cardiovascular Risk Assessment

KW - MORGAM

KW - EU

KW - CORONARY-ARTERY-DISEASE

KW - CARDIOVASCULAR-DISEASE

KW - MYOCARDIAL-INFARCTION

KW - VASCULAR EVENTS

KW - RISK

KW - BIOMARKERS

KW - PREDICTION

KW - PROTEIN

KW - PROGNOSIS

KW - DISCOVERY

U2 - 10.1007/s10654-014-9952-x.

DO - 10.1007/s10654-014-9952-x.

M3 - Article

C2 - 25238720

SN - 0393-2990

VL - 29

SP - 777

EP - 790

JO - European Journal of Epidemiology

JF - European Journal of Epidemiology

IS - 10

ER -

BiomarCaRE: rationale and design of the European BiomarCaRE project including 300,000 participants from 13 European countries

Abstract

Keywords

Access to Document

Fingerprint

Cite this