Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than by RTX

A.W. Pawluczkowycz; F.J. Beurskens; P.V. Beum; M.A. Lindorfer; J.G.J. van de Winkel; P.W.H.I. Parren; R.P. Taylor

Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than by RTX

Translated title of the contribution: Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than by RTX

A.W. Pawluczkowycz
, F.J. Beurskens
, P.V. Beum
, M.A. Lindorfer
, J.G.J. van de Winkel
, P.W.H.I. Parren
, R.P. Taylor

Research output: Contribution to journal › Article › Academic › peer-review

Translated title of the contribution	Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than by RTX
Original language	Undefined/Unknown
Pages (from-to)	749-758
Number of pages	10
Journal	Journal of Immunology
Volume	183
Publication status	Published - 2009

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Cite this

Pawluczkowycz, A. W., Beurskens, F. J., Beum, P. V., Lindorfer, M. A., van de Winkel, J. G. J., Parren, P. W. H. I., & Taylor, R. P. (2009). Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than by RTX. Journal of Immunology, 183, 749-758. http://www.jimmunol.org/cgi/content/full/183/1/749

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title = "Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than by RTX",

author = "A.W. Pawluczkowycz and F.J. Beurskens and P.V. Beum and M.A. Lindorfer and \{van de Winkel\}, J.G.J. and P.W.H.I. Parren and R.P. Taylor",

year = "2009",

language = "Undefined/Unknown",

volume = "183",

pages = "749--758",

journal = "Journal of Immunology",

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Pawluczkowycz, AW, Beurskens, FJ, Beum, PV, Lindorfer, MA, van de Winkel, JGJ, Parren, PWHI & Taylor, RP 2009, 'Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than by RTX', Journal of Immunology, vol. 183, pp. 749-758. <http://www.jimmunol.org/cgi/content/full/183/1/749>

Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than by RTX. / Pawluczkowycz, A.W.; Beurskens, F.J.; Beum, P.V. et al.
In: Journal of Immunology, Vol. 183, 2009, p. 749-758.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than by RTX

AU - Pawluczkowycz, A.W.

AU - Beurskens, F.J.

AU - Beum, P.V.

AU - Lindorfer, M.A.

AU - van de Winkel, J.G.J.

AU - Parren, P.W.H.I.

AU - Taylor, R.P.

PY - 2009

Y1 - 2009

M3 - Article

SN - 0022-1767

VL - 183

SP - 749

EP - 758

JO - Journal of Immunology

JF - Journal of Immunology

ER -