Abstract
Since the introduction of modern analysers, more and more labs switch from manual to automated methods for the determination of estradiol, testosterone, LH and FSH. However, this resulted in an increase in variation between the laboratories, above all with estradiol and testosterone at lower concentrations. A retrospective analysis of the LWBA 2005 and 2006 data, the data of the Deutsche Ringversuch and the UK NEQAS data, showed that the automation of the peptid hormones LH and FSH yielded good results, whereas the estradiol and testosterone determinations remain to be a concern, especially at the lower ranges (<0.2 nmol/l for estradiol, <5 nmol/l for testosterone). One should consider using manual methods for the determination of these hormones at lower concentrations.
Translated title of the contribution | Determination of fertility hormones anno 2006 |
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Original language | Dutch |
Pages (from-to) | 42-46 |
Number of pages | 5 |
Journal | Nederlands Tijdschrift voor Klinische Chemie en Laboratoriumgeneeskunde |
Volume | 32 |
Issue number | 1 |
Publication status | Published - 1 Jan 2007 |
Keywords
- Fertility hormones