Beleid bij verhoogde serumwaarden van aminotransferasen zonder symptomen, in het bijzonder bij non-alcoholische steatohepatitis

B. Oldenburg; G. P. Van Berge Henegouwen

Beleid bij verhoogde serumwaarden van aminotransferasen zonder symptomen, in het bijzonder bij non-alcoholische steatohepatitis

Translated title of the contribution: Management in increased serum aminotransferase levels without symptoms in particular in nonalcoholic steatohepatitis

B. Oldenburg^*
, G. P. Van Berge Henegouwen

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

5 Citations (Scopus)

Abstract

At routine determination of serum activities of transaminases (aspartate aminotransferase (ASAT) and alanine aminotransferase (ALAT)) increased levels are frequently found. - An algorithm may be used in the analysis of elevated transaminase levels: after elimination of the most frequent causes of hepatitis (alcoholic hepatitis, chronic hepatitis B and C) and some rare conditions (autoimmune hepatitis, α ₁-antitrypsin deficiency, haemochromatosis and Wilson's disease), the diagnosis will often be nonalcoholic steatohepatitis. - Although nonalcoholic steatohepatitis is considered a stable disease, recent literature shows a progression to cirrhosis in 8-17%. - So far, no effective therapeutic strategies are available for nonalcoholic steatohepatitis.

Translated title of the contribution	Management in increased serum aminotransferase levels without symptoms in particular in nonalcoholic steatohepatitis
Original language	Dutch
Pages (from-to)	506-509
Number of pages	4
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	143
Issue number	10
Publication status	Published - 6 Mar 1999

Cite this

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title = "Beleid bij verhoogde serumwaarden van aminotransferasen zonder symptomen, in het bijzonder bij non-alcoholische steatohepatitis",

abstract = "At routine determination of serum activities of transaminases (aspartate aminotransferase (ASAT) and alanine aminotransferase (ALAT)) increased levels are frequently found. - An algorithm may be used in the analysis of elevated transaminase levels: after elimination of the most frequent causes of hepatitis (alcoholic hepatitis, chronic hepatitis B and C) and some rare conditions (autoimmune hepatitis, α 1-antitrypsin deficiency, haemochromatosis and Wilson's disease), the diagnosis will often be nonalcoholic steatohepatitis. - Although nonalcoholic steatohepatitis is considered a stable disease, recent literature shows a progression to cirrhosis in 8-17\%. - So far, no effective therapeutic strategies are available for nonalcoholic steatohepatitis.",

author = "B. Oldenburg and \{Van Berge Henegouwen\}, \{G. P.\}",

year = "1999",

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language = "Dutch",

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TY - JOUR

T1 - Beleid bij verhoogde serumwaarden van aminotransferasen zonder symptomen, in het bijzonder bij non-alcoholische steatohepatitis

AU - Oldenburg, B.

AU - Van Berge Henegouwen, G. P.

PY - 1999/3/6

Y1 - 1999/3/6

N2 - At routine determination of serum activities of transaminases (aspartate aminotransferase (ASAT) and alanine aminotransferase (ALAT)) increased levels are frequently found. - An algorithm may be used in the analysis of elevated transaminase levels: after elimination of the most frequent causes of hepatitis (alcoholic hepatitis, chronic hepatitis B and C) and some rare conditions (autoimmune hepatitis, α 1-antitrypsin deficiency, haemochromatosis and Wilson's disease), the diagnosis will often be nonalcoholic steatohepatitis. - Although nonalcoholic steatohepatitis is considered a stable disease, recent literature shows a progression to cirrhosis in 8-17%. - So far, no effective therapeutic strategies are available for nonalcoholic steatohepatitis.

AB - At routine determination of serum activities of transaminases (aspartate aminotransferase (ASAT) and alanine aminotransferase (ALAT)) increased levels are frequently found. - An algorithm may be used in the analysis of elevated transaminase levels: after elimination of the most frequent causes of hepatitis (alcoholic hepatitis, chronic hepatitis B and C) and some rare conditions (autoimmune hepatitis, α 1-antitrypsin deficiency, haemochromatosis and Wilson's disease), the diagnosis will often be nonalcoholic steatohepatitis. - Although nonalcoholic steatohepatitis is considered a stable disease, recent literature shows a progression to cirrhosis in 8-17%. - So far, no effective therapeutic strategies are available for nonalcoholic steatohepatitis.

UR - https://www.scopus.com/pages/publications/0033528515

M3 - Review article

C2 - 10321258

AN - SCOPUS:0033528515

SN - 0028-2162

VL - 143

SP - 506

EP - 509

JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

IS - 10

ER -

Beleid bij verhoogde serumwaarden van aminotransferasen zonder symptomen, in het bijzonder bij non-alcoholische steatohepatitis

Abstract

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