Bayesian model selection for pathological data.

Carole H. Sudre*, Manuel Jorge Cardoso, Willem Bouvy, Geert Jan Biessels, Josephine Barnes, Sébastien Ourselin

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Abstract

The detection of abnormal intensities in brain images caused by the presence of pathologies is currently under great scrutiny. Selecting appropriate models for pathological data is of critical importance for an unbiased and biologically plausible model fit, which in itself enables a better understanding of the underlying data and biological processes. Besides, it impacts on one's ability to extract pathologically meaningful imaging biomarkers. With this aim in mind, this work proposes a fully unsupervised hierarchical model selection framework for neuroimaging data which permits the stratification of different types of abnormal image atterns without prior knowledge about the subject's pathological status.

Original languageEnglish
Title of host publicationMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Pages323-330
Number of pages8
Volume17
EditionPt 1
Publication statusPublished - 2014

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