Awareness in dementia: a review of clinical correlates

Pauline Aalten, Evelien van Valen, Linda Clare, Geraldine Kenny, Frans Verhey

Research output: Contribution to journalReview articlepeer-review

Abstract

This article provides a review of the literature on clinical correlates of awareness in dementia. Most inconsistencies were found with regard to an association between depression and higher levels of awareness. Dysthymia, but not major depression, is probably related to higher levels of awareness. Anxiety also appears to be related to higher levels of awareness. Apathy and psychosis are frequently present in patients with less awareness, and may share common neuropathological substrates with awareness. Furthermore, unawareness seems to be related to difficulties in daily life functioning, increased caregiver burden, and deterioration in global dementia severity. Factors that may be of influence on the inconclusive data are discussed, as are future directions of research.

Original languageEnglish
Pages (from-to)414-22
Number of pages9
JournalAging & Mental Health
Volume9
Issue number5
DOIs
Publication statusPublished - Sept 2005

Keywords

  • Activities of Daily Living
  • Affect
  • Anxiety
  • Caregivers/psychology
  • Cognition
  • Dementia/psychology
  • Depression
  • Humans
  • Self Concept
  • Severity of Illness Index

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