TY - JOUR
T1 - Automated CT quantification methods for the assessment of interstitial lung disease in collagen vascular diseases
T2 - A systematic review
AU - van Royen, Florien S.
AU - Moll, Sofia A.
AU - van Laar, Jacob M.
AU - van Montfrans, Joris M.
AU - de Jong, Pim A.
AU - Mohamed Hoesein, Firdaus A.A.
N1 - Funding Information:
None.
Publisher Copyright:
© 2019 Elsevier B.V.
PY - 2019/3/1
Y1 - 2019/3/1
N2 -
Interstitial lung disease (ILD) is highly prevalent in collagen vascular diseases and reduction of ILD is an important therapeutic target. To that end, reliable quantification of pulmonary disease severity is of great significance. This study systematically reviewed the literature on automated computed tomography (CT) quantification methods for assessing ILD in collagen vascular diseases. PRISMA-DTA guidelines for systematic reviews were used and 19 original research articles up to January 2018 were included based on a MEDLINE/Pubmed and Embase search. Quantitative CT methods were categorized as histogram assessment (12 studies) or pattern/texture recognition (7 studies). R
2
for correlation with visual ILD scoring ranged from 0.143 (p < 0.01) to 0.687 (p < 0.0001), for FVC from 0.048 (p < 0.0001) to 0.504 (p < 0.0001) and for DLCO from 0.015 (p = 0.61) to 0.449 (p < 0.0001). Automated CT methods are independent of reader's expertise and are a promising tool in the quantification of ILD in collagen vascular disease patients.
AB -
Interstitial lung disease (ILD) is highly prevalent in collagen vascular diseases and reduction of ILD is an important therapeutic target. To that end, reliable quantification of pulmonary disease severity is of great significance. This study systematically reviewed the literature on automated computed tomography (CT) quantification methods for assessing ILD in collagen vascular diseases. PRISMA-DTA guidelines for systematic reviews were used and 19 original research articles up to January 2018 were included based on a MEDLINE/Pubmed and Embase search. Quantitative CT methods were categorized as histogram assessment (12 studies) or pattern/texture recognition (7 studies). R
2
for correlation with visual ILD scoring ranged from 0.143 (p < 0.01) to 0.687 (p < 0.0001), for FVC from 0.048 (p < 0.0001) to 0.504 (p < 0.0001) and for DLCO from 0.015 (p = 0.61) to 0.449 (p < 0.0001). Automated CT methods are independent of reader's expertise and are a promising tool in the quantification of ILD in collagen vascular disease patients.
KW - Computed tomography, X ray
KW - Connective tissue diseases
KW - Lung diseases, Interstitial
KW - Systematic review
KW - Lung Diseases, Interstitial/diagnostic imaging
KW - Lung/diagnostic imaging
KW - Tomography, X-Ray Computed/methods
KW - Humans
KW - Collagen Diseases/diagnostic imaging
KW - Vascular Diseases/diagnostic imaging
UR - http://www.scopus.com/inward/record.url?scp=85060699539&partnerID=8YFLogxK
U2 - 10.1016/j.ejrad.2019.01.024
DO - 10.1016/j.ejrad.2019.01.024
M3 - Review article
C2 - 30777211
AN - SCOPUS:85060699539
SN - 0720-048X
VL - 112
SP - 200
EP - 206
JO - European Journal of Radiology
JF - European Journal of Radiology
ER -