TY - JOUR
T1 - Association of Hearing Impairment with Incident Depressive Symptoms
T2 - A Community-Based Prospective Study
AU - Lisan, Quentin
AU - van Sloten, Thomas T
AU - Lemogne, Cédric
AU - Offredo, Lucille
AU - Climie, Rachel E
AU - Boutouyrie, Pierre
AU - Guibout, Catherine
AU - Thomas, Frédérique
AU - Danchin, Nicolas
AU - Jouven, Xavier
AU - Empana, Jen-Philippe
N1 - Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/12
Y1 - 2019/12
N2 - OBJECTIVE: The aim was to investigate the potential association between hearing impairment and incident depressive symptoms.METHODS: Using a prospective community-based cohort study in France (the Paris Prospective Study III), participants aged 50-75 years were recruited between 2008 and 2012 and thereafter followed up every 2 years up to 2018. Hearing impairment, measured at study recruitment by audiometry testing, was defined as a pure tone average >25 decibels in the better ear. Incident depressive symptoms, measured using the validated 13-item Questionnaire of Depression 2nd version, was assessed during follow-up. Multivariate generalized estimating equations were used to compute odds ratio (OR) and 95% confidence intervals (CI).RESULTS: Among 7591 participants free of depressive symptoms at baseline (mean age 59.8 years, 63% of men), 14.3% had hearing impairment. Over 6 years of follow-up, 479 subjects (6.3%) had incident depressive symptoms. The OR for incident depressive symptoms was 1.36 for subjects with baseline hearing impairment (95% CI, 1.06-1.73). A pooled analysis of 4 published prospective studies yielded a multivariable relative risk of baseline hearing impairment for incident depressive symptoms of 1.29 (95% CI, 1.09-1.53).CONCLUSIONS: In this community-based prospective cohort study of participants aged 50 to 75 years, baseline hearing impairment was associated with a 36% increased odds of incident depressive symptoms.
AB - OBJECTIVE: The aim was to investigate the potential association between hearing impairment and incident depressive symptoms.METHODS: Using a prospective community-based cohort study in France (the Paris Prospective Study III), participants aged 50-75 years were recruited between 2008 and 2012 and thereafter followed up every 2 years up to 2018. Hearing impairment, measured at study recruitment by audiometry testing, was defined as a pure tone average >25 decibels in the better ear. Incident depressive symptoms, measured using the validated 13-item Questionnaire of Depression 2nd version, was assessed during follow-up. Multivariate generalized estimating equations were used to compute odds ratio (OR) and 95% confidence intervals (CI).RESULTS: Among 7591 participants free of depressive symptoms at baseline (mean age 59.8 years, 63% of men), 14.3% had hearing impairment. Over 6 years of follow-up, 479 subjects (6.3%) had incident depressive symptoms. The OR for incident depressive symptoms was 1.36 for subjects with baseline hearing impairment (95% CI, 1.06-1.73). A pooled analysis of 4 published prospective studies yielded a multivariable relative risk of baseline hearing impairment for incident depressive symptoms of 1.29 (95% CI, 1.09-1.53).CONCLUSIONS: In this community-based prospective cohort study of participants aged 50 to 75 years, baseline hearing impairment was associated with a 36% increased odds of incident depressive symptoms.
KW - Cohort study
KW - Depressive symptoms
KW - Hearing impairment
KW - Prospective
UR - http://www.scopus.com/inward/record.url?scp=85068752140&partnerID=8YFLogxK
U2 - 10.1016/j.amjmed.2019.05.039
DO - 10.1016/j.amjmed.2019.05.039
M3 - Article
C2 - 31247178
SN - 0002-9343
VL - 132
SP - 1441-1449.e4
JO - The American Journal of Medicine
JF - The American Journal of Medicine
IS - 12
ER -