TY - JOUR
T1 - Association between lesion location and sensorimotor rhythms in stroke - a systematic review with narrative synthesis
AU - Kancheva, Ivana
AU - van der Salm, Sandra M A
AU - Ramsey, Nick F
AU - Vansteensel, Mariska J
N1 - Funding Information:
The authors would like to acknowledge the contribution of Utrecht University librarian Drs. Paulien H. Wiersma who helped improve the developed systematic literature search strategy, a key aspect of this work. This research was funded by the National Institute on Deafness and Other Communication Disorders (U01DC016686). The funding source was not involved in the design or writing of this manuscript.
Publisher Copyright:
© 2023, The Author(s).
PY - 2023/12
Y1 - 2023/12
N2 - BACKGROUND: Stroke causes alterations in the sensorimotor rhythms (SMRs) of the brain. However, little is known about the influence of lesion location on the SMRs. Understanding this relationship is relevant for the use of SMRs in assistive and rehabilitative therapies, such as Brain-Computer Interfaces (BCIs)..METHODS: We reviewed current evidence on the association between stroke lesion location and SMRs through systematically searching PubMed and Embase and generated a narrative synthesis of findings.RESULTS: We included 12 articles reporting on 161 patients. In resting-state studies, cortical and pontine damage were related to an overall decrease in alpha (∼8-12 Hz) and increase in delta (∼1-4 Hz) power. In movement paradigm studies, attenuated alpha and beta (∼15-25 Hz) event-related desynchronization (ERD) was shown in stroke patients during (attempted) paretic hand movement, compared to controls. Stronger reductions in alpha and beta ERD in the ipsilesional, compared to contralesional hemisphere, were observed for cortical lesions. Subcortical stroke was found to affect bilateral ERD and ERS, but results were highly variable.CONCLUSIONS: Findings suggest a link between stroke lesion location and SMR alterations, but heterogeneity across studies and limited lesion location descriptions precluded a meta-analysis.SIGNIFICANCE: Future research would benefit from more uniformly defined outcome measures, homogeneous methodologies, and improved lesion location reporting.
AB - BACKGROUND: Stroke causes alterations in the sensorimotor rhythms (SMRs) of the brain. However, little is known about the influence of lesion location on the SMRs. Understanding this relationship is relevant for the use of SMRs in assistive and rehabilitative therapies, such as Brain-Computer Interfaces (BCIs)..METHODS: We reviewed current evidence on the association between stroke lesion location and SMRs through systematically searching PubMed and Embase and generated a narrative synthesis of findings.RESULTS: We included 12 articles reporting on 161 patients. In resting-state studies, cortical and pontine damage were related to an overall decrease in alpha (∼8-12 Hz) and increase in delta (∼1-4 Hz) power. In movement paradigm studies, attenuated alpha and beta (∼15-25 Hz) event-related desynchronization (ERD) was shown in stroke patients during (attempted) paretic hand movement, compared to controls. Stronger reductions in alpha and beta ERD in the ipsilesional, compared to contralesional hemisphere, were observed for cortical lesions. Subcortical stroke was found to affect bilateral ERD and ERS, but results were highly variable.CONCLUSIONS: Findings suggest a link between stroke lesion location and SMR alterations, but heterogeneity across studies and limited lesion location descriptions precluded a meta-analysis.SIGNIFICANCE: Future research would benefit from more uniformly defined outcome measures, homogeneous methodologies, and improved lesion location reporting.
KW - Brain-Computer Interfaces
KW - Lesion location
KW - Motor recovery
KW - Sensorimotor rhythms
KW - Stroke
KW - Systematic review
UR - http://www.scopus.com/inward/record.url?scp=85168586073&partnerID=8YFLogxK
U2 - 10.1007/s10072-023-06982-8
DO - 10.1007/s10072-023-06982-8
M3 - Review article
C2 - 37606742
SN - 1590-1874
VL - 44
SP - 4263
EP - 4289
JO - Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
JF - Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
IS - 12
ER -