Abstract
Online postdilution hemodiafiltration (HDF) has been related to an improved patient survival as compared to HD, especially when high convection volumes are applied. Apart from this favorable result, however, online-HDF may evoke side effects that may counteract part of its benefits. Moreover, specific draw backs, related to the set up and maintenance phases of HDF treatment, may hinder the implementation of online HDF on a large scale. So, what are the disadvantages when performing HDF in every day clinical practice? From a medical perspective these may include safety concerns related to the large amounts of substitution fluids directly infused into the patients, the unintended removal of nutrients and other useful compounds including medication, and activation of blood cells. From a financial perspective additional costs may be of relevance. From a practical perspective the main downside of HDF is that starting up a HDF program needs extra efforts of the dialysis staff. In this chapter we discuss the above mentioned issues.
| Original language | English |
|---|---|
| Title of host publication | Hemodiafiltration |
| Subtitle of host publication | Theory, Technology and Clinical Practice |
| Publisher | Springer International Publishing AG |
| Pages | 279-288 |
| Number of pages | 10 |
| ISBN (Electronic) | 9783319233321 |
| ISBN (Print) | 9783319233314 |
| DOIs | |
| Publication status | Published - 10 Nov 2015 |
Keywords
- Disadvantages
- Hemodiafiltration
- Safety
- Side effects