Antimicrobial resistance of Neisseria gonorrhoeae and emerging ciprofloxacin resistance in the Netherlands, 1991 to 1998

A J de Neeling, M van Santen-Verheuvel, J Spaargaren, R J Willems

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Surveillance of antibiotic resistance in Neisseria gonorrhoeae showed a decrease in the percentage of beta-lactamase-producing isolates but an increase in intermediately penicillin-resistant strains and strains resistant to a high level of tetracycline. MICs for the ciprofloxacin-resistant isolates that emerged increased, and these isolates had mutations in gyrA and parC similar to those observed in the Far East.

Original languageEnglish
Pages (from-to)3184-5
Number of pages2
JournalAntimicrobial Agents and Chemotherapy
Volume44
Issue number11
Publication statusPublished - Nov 2000

Keywords

  • Anti-Infective Agents
  • Ciprofloxacin
  • DNA Gyrase
  • DNA Topoisomerase IV
  • DNA Topoisomerases, Type II
  • Drug Resistance, Microbial
  • Humans
  • Microbial Sensitivity Tests
  • Neisseria gonorrhoeae
  • Netherlands
  • beta-Lactamases
  • Journal Article

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