Antibodies and methods of use thereof in treatment of bacteria

SHM Rooijakkers; Annemarie Kuipers; CPM van Kessel; JA van Strijp; Janine Schuurman; frank beurskens; paul parren; kristin strumane; rob de jong

Antibodies and methods of use thereof in treatment of bacteria

SHM Rooijakkers (Inventor)
, Annemarie Kuipers (Inventor)
, CPM van Kessel (Inventor)
, JA van Strijp (Inventor)
, Janine Schuurman (Inventor)
, frank beurskens (Inventor)
, paul parren (Inventor)
, kristin strumane (Inventor)
, rob de jong (Inventor)

Research output: Patent › Academic

Abstract

The present invention relates to antibody molecules that bind to Wall Teichoic Acid (WTA) or Capsular Polysaccharides (CP) such as Capsular Polysaccharides type 5 (CP5). The invention relates in particular to antibody molecules of the IgG isotype having a mutation in the Fc domain that enhances clustering of IgG molecules after target binding. The invention also relates to pharmaceutical compositions containing these molecules and the treatment of infectious diseases using these compositions

Original language	English
Publication status	Published - 2017

Cite this

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title = "Antibodies and methods of use thereof in treatment of bacteria",

abstract = "The present invention relates to antibody molecules that bind to Wall Teichoic Acid (WTA) or Capsular Polysaccharides (CP) such as Capsular Polysaccharides type 5 (CP5). The invention relates in particular to antibody molecules of the IgG isotype having a mutation in the Fc domain that enhances clustering of IgG molecules after target binding. The invention also relates to pharmaceutical compositions containing these molecules and the treatment of infectious diseases using these compositions",

author = "SHM Rooijakkers and Annemarie Kuipers and \{van Kessel\}, CPM and \{van Strijp\}, JA and Janine Schuurman and frank beurskens and paul parren and kristin strumane and \{de jong\}, rob",

year = "2017",

language = "English",

type = "Patent",

}

TY - PAT

T1 - Antibodies and methods of use thereof in treatment of bacteria

AU - Rooijakkers, SHM

AU - Kuipers, Annemarie

AU - van Kessel, CPM

AU - van Strijp, JA

AU - Schuurman, Janine

AU - beurskens, frank

AU - parren, paul

AU - strumane, kristin

AU - de jong, rob

PY - 2017

Y1 - 2017

N2 - The present invention relates to antibody molecules that bind to Wall Teichoic Acid (WTA) or Capsular Polysaccharides (CP) such as Capsular Polysaccharides type 5 (CP5). The invention relates in particular to antibody molecules of the IgG isotype having a mutation in the Fc domain that enhances clustering of IgG molecules after target binding. The invention also relates to pharmaceutical compositions containing these molecules and the treatment of infectious diseases using these compositions

AB - The present invention relates to antibody molecules that bind to Wall Teichoic Acid (WTA) or Capsular Polysaccharides (CP) such as Capsular Polysaccharides type 5 (CP5). The invention relates in particular to antibody molecules of the IgG isotype having a mutation in the Fc domain that enhances clustering of IgG molecules after target binding. The invention also relates to pharmaceutical compositions containing these molecules and the treatment of infectious diseases using these compositions

M3 - Patent

ER -

Antibodies and methods of use thereof in treatment of bacteria

Abstract

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