Androgens as adjuvant treatment in postmenopausal female patients with rheumatoid arthritis

A. Booij; C. M. Biewenga-Booij; O. Huber-Bruning; C. Cornelis; J. W.G. Jacobs; J. W.J. Bijlsma

Androgens as adjuvant treatment in postmenopausal female patients with rheumatoid arthritis

A. Booij, C. M. Biewenga-Booij, O. Huber-Bruning, C. Cornelis, J. W.G. Jacobs, J. W.J. Bijlsma^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Objective - To examine the possible beneficial effect of androgens in postmenopausal women with active rheumatoid arthritis. Methods - 107 women participated in a double blind placebo controlled trial to evaluate the effect of 50 mg testosterone propionate intramuscularly every two weeks for one year. Results - An improvement in ESR, Dutch health assessment questionnaire, and pain was noted. In addition, 21% of patients treated with testosterone fulfilled the ACR improvement criteria after one year, versus only 4% of the placebo group. The treatment was well tolerated. Conclusions - Testosterone may improve the general wellbeing of postmenopausal women with active rheumatoid arthritis.

Original language	English
Pages (from-to)	811-815
Number of pages	5
Journal	Annals of the Rheumatic Diseases
Volume	55
Issue number	11
Publication status	Published - 3 Dec 1996

Cite this

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title = "Androgens as adjuvant treatment in postmenopausal female patients with rheumatoid arthritis",

abstract = "Objective - To examine the possible beneficial effect of androgens in postmenopausal women with active rheumatoid arthritis. Methods - 107 women participated in a double blind placebo controlled trial to evaluate the effect of 50 mg testosterone propionate intramuscularly every two weeks for one year. Results - An improvement in ESR, Dutch health assessment questionnaire, and pain was noted. In addition, 21% of patients treated with testosterone fulfilled the ACR improvement criteria after one year, versus only 4% of the placebo group. The treatment was well tolerated. Conclusions - Testosterone may improve the general wellbeing of postmenopausal women with active rheumatoid arthritis.",

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AU - Booij, A.

AU - Biewenga-Booij, C. M.

AU - Huber-Bruning, O.

AU - Cornelis, C.

AU - Jacobs, J. W.G.

AU - Bijlsma, J. W.J.

PY - 1996/12/3

Y1 - 1996/12/3

N2 - Objective - To examine the possible beneficial effect of androgens in postmenopausal women with active rheumatoid arthritis. Methods - 107 women participated in a double blind placebo controlled trial to evaluate the effect of 50 mg testosterone propionate intramuscularly every two weeks for one year. Results - An improvement in ESR, Dutch health assessment questionnaire, and pain was noted. In addition, 21% of patients treated with testosterone fulfilled the ACR improvement criteria after one year, versus only 4% of the placebo group. The treatment was well tolerated. Conclusions - Testosterone may improve the general wellbeing of postmenopausal women with active rheumatoid arthritis.

AB - Objective - To examine the possible beneficial effect of androgens in postmenopausal women with active rheumatoid arthritis. Methods - 107 women participated in a double blind placebo controlled trial to evaluate the effect of 50 mg testosterone propionate intramuscularly every two weeks for one year. Results - An improvement in ESR, Dutch health assessment questionnaire, and pain was noted. In addition, 21% of patients treated with testosterone fulfilled the ACR improvement criteria after one year, versus only 4% of the placebo group. The treatment was well tolerated. Conclusions - Testosterone may improve the general wellbeing of postmenopausal women with active rheumatoid arthritis.

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JO - Annals of the Rheumatic Diseases

JF - Annals of the Rheumatic Diseases

IS - 11

ER -

Androgens as adjuvant treatment in postmenopausal female patients with rheumatoid arthritis

Abstract

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