Analysis of differences between conditioned and control reflex series in EMG recordings

H. W. van der Glas*, J. H. Abbink, A. van der Bilt, S. W. Cadden

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    17 Citations (Scopus)


    Two methods are presented for the data analysis of signals derived by subtracting conditioned from control reflex data in full-wave rectified and averaged electromyographic (EMG) signals. The first method uses the ratios of the mean amplitudes and standard errors of the mean (S.E.M.s) (i.e. Student's t values) of a series of data points in such a difference signal, and deals with the detection of latencies of reflex components which are susceptible to a conditioning stimulus or experimental situation. The second method applies a modified cumulative sum (CUSUM) technique to full-wave rectified difference signals. This modified CUSUM technique determines the magnitude of the effects of the conditioning situation above that expected due to chance fluctuations, taking into account the effect of reflex modulations on such chance fluctuations in a post-stimulus period. The modified CUSUM technique proved particularly useful when various subtle but consistent, opposing changes occurred sequentially in the conditioned series thus yielding a complicated pattern of effects in a difference signal, with a low signal-to-noise ratio.

    Original languageEnglish
    Pages (from-to)117-125
    Number of pages9
    JournalJournal of Neuroscience Methods
    Issue number1-2
    Publication statusPublished - 1995


    • (Human)
    • Conditioning
    • CUSUM
    • Electromyography
    • Reflex analysis
    • Significance testing


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