An NSF-like ATPase, p97, and NSF mediate cisternal regrowth from mitotic golgi fragments

Catherine Rabouille*, Timothy P. Levine, Jan Michael Peters, Graham Warren

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

297 Citations (Scopus)

Abstract

Golgi cisternae regrew in a cell-free system from mitotic Golgi fragments incubated with buffer alone. Pretreatment with NEM or salt washing inhibited regrowth, but this could be restored either by p97, an NSF-like ATPase, or by NSF together with SNAPs and p115, a vesicle docking protein. The morphology of cisternae regrown with p97 and NSF-SNAPs-p115 differed, suggesting that they play distinct roles in rebuilding Golgi cisternae after mitosis.

Original languageEnglish
Pages (from-to)905-914
Number of pages10
JournalCell
Volume82
Issue number6
DOIs
Publication statusPublished - 22 Sept 1995

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