Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk

Mignon T. van den Elzen; Harmieke van Os-Medendorp; Heike Röckmann-Helmbach; Els van Hoffen; Ans F M Lebens; Helma van Doorn; Rob J B Klemans; Carla A F M Bruijnzeel-Koomen; C. Erik Hack; Leonard Kaufman; Anurag Relan; André C. Knulst

doi:10.1016/j.jaci.2016.04.019

Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk

Mignon T. van den Elzen^*
, Harmieke van Os-Medendorp
, Heike Röckmann-Helmbach
, Els van Hoffen
, Ans F M Lebens
, Helma van Doorn
, Rob J B Klemans
, Carla A F M Bruijnzeel-Koomen
, C. Erik Hack
, Leonard Kaufman
, Anurag Relan
, André C. Knulst

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Background Recombinant human C1 inhibitor (rhC1INH) for on-demand treatment of hereditary angioedema is purified from milk of transgenic rabbits. It contains low amounts (

Original language	English
Pages (from-to)	476-481.e1
Journal	Journal of Allergy and Clinical Immunology
Volume	138
Issue number	2
DOIs	https://doi.org/10.1016/j.jaci.2016.04.019
Publication status	Published - 1 Aug 2016

Keywords

allergenicity
cow's milk allergy
Hereditary angioedema
intracutaneous test
intradermal testing
rabbit allergy
recombinant human C1 esterase inhibitor
skin prick test
subcutaneous administration
subcutaneous challenge

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10.1016/j.jaci.2016.04.019

09-mainFinal published version, 345 KBLicence: Taverne

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van den Elzen, M. T., van Os-Medendorp, H., Röckmann-Helmbach, H., van Hoffen, E., Lebens, A. F. M., van Doorn, H., Klemans, R. J. B., Bruijnzeel-Koomen, C. A. F. M., Hack, C. E., Kaufman, L., Relan, A., & Knulst, A. C. (2016). Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk. Journal of Allergy and Clinical Immunology, 138(2), 476-481.e1. https://doi.org/10.1016/j.jaci.2016.04.019

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title = "Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk",

abstract = "Background Recombinant human C1 inhibitor (rhC1INH) for on-demand treatment of hereditary angioedema is purified from milk of transgenic rabbits. It contains low amounts (",

keywords = "allergenicity, cow's milk allergy, Hereditary angioedema, intracutaneous test, intradermal testing, rabbit allergy, recombinant human C1 esterase inhibitor, skin prick test, subcutaneous administration, subcutaneous challenge",

author = "\{van den Elzen\}, \{Mignon T.\} and \{van Os-Medendorp\}, Harmieke and Heike R{\"o}ckmann-Helmbach and \{van Hoffen\}, Els and Lebens, \{Ans F M\} and \{van Doorn\}, Helma and Klemans, \{Rob J B\} and Bruijnzeel-Koomen, \{Carla A F M\} and Hack, \{C. Erik\} and Leonard Kaufman and Anurag Relan and Knulst, \{Andr{\'e} C.\}",

year = "2016",

month = aug,

day = "1",

doi = "10.1016/j.jaci.2016.04.019",

language = "English",

volume = "138",

pages = "476--481.e1",

journal = "Journal of Allergy and Clinical Immunology",

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van den Elzen, MT, van Os-Medendorp, H, Röckmann-Helmbach, H, van Hoffen, E, Lebens, AFM, van Doorn, H, Klemans, RJB, Bruijnzeel-Koomen, CAFM, Hack, CE, Kaufman, L, Relan, A & Knulst, AC 2016, 'Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk', Journal of Allergy and Clinical Immunology, vol. 138, no. 2, pp. 476-481.e1. https://doi.org/10.1016/j.jaci.2016.04.019

Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk. / van den Elzen, Mignon T.; van Os-Medendorp, Harmieke; Röckmann-Helmbach, Heike et al.
In: Journal of Allergy and Clinical Immunology, Vol. 138, No. 2, 01.08.2016, p. 476-481.e1.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk

AU - van den Elzen, Mignon T.

AU - van Os-Medendorp, Harmieke

AU - Röckmann-Helmbach, Heike

AU - van Hoffen, Els

AU - Lebens, Ans F M

AU - van Doorn, Helma

AU - Klemans, Rob J B

AU - Bruijnzeel-Koomen, Carla A F M

AU - Hack, C. Erik

AU - Kaufman, Leonard

AU - Relan, Anurag

AU - Knulst, André C.

PY - 2016/8/1

Y1 - 2016/8/1

N2 - Background Recombinant human C1 inhibitor (rhC1INH) for on-demand treatment of hereditary angioedema is purified from milk of transgenic rabbits. It contains low amounts (

AB - Background Recombinant human C1 inhibitor (rhC1INH) for on-demand treatment of hereditary angioedema is purified from milk of transgenic rabbits. It contains low amounts (

KW - allergenicity

KW - cow's milk allergy

KW - Hereditary angioedema

KW - intracutaneous test

KW - intradermal testing

KW - rabbit allergy

KW - recombinant human C1 esterase inhibitor

KW - skin prick test

KW - subcutaneous administration

KW - subcutaneous challenge

UR - https://www.scopus.com/pages/publications/84990828662

U2 - 10.1016/j.jaci.2016.04.019

DO - 10.1016/j.jaci.2016.04.019

M3 - Article

C2 - 27321437

AN - SCOPUS:84990828662

SN - 0091-6749

VL - 138

SP - 476-481.e1

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

IS - 2

ER -

Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk

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Keywords

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