Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk

Mignon T. van den Elzen; Harmieke van Os-Medendorp; Heike Röckmann-Helmbach; Els van Hoffen; Ans F M Lebens; Helma van Doorn; Rob J B Klemans; Carla A F M Bruijnzeel-Koomen; C. Erik Hack; Leonard Kaufman; Anurag Relan; André C. Knulst

doi:10.1016/j.jaci.2016.04.019

Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk

Mignon T. van den Elzen^*, Harmieke van Os-Medendorp, Heike Röckmann-Helmbach, Els van Hoffen, Ans F M Lebens, Helma van Doorn, Rob J B Klemans, Carla A F M Bruijnzeel-Koomen, C. Erik Hack, Leonard Kaufman, Anurag Relan, André C. Knulst

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Background Recombinant human C1 inhibitor (rhC1INH) for on-demand treatment of hereditary angioedema is purified from milk of transgenic rabbits. It contains low amounts (

Original language	English
Pages (from-to)	476-481.e1
Journal	Journal of Allergy and Clinical Immunology
Volume	138
Issue number	2
DOIs	https://doi.org/10.1016/j.jaci.2016.04.019
Publication status	Published - 1 Aug 2016

Keywords

allergenicity
cow's milk allergy
Hereditary angioedema
intracutaneous test
intradermal testing
rabbit allergy
recombinant human C1 esterase inhibitor
skin prick test
subcutaneous administration
subcutaneous challenge

Access to Document

10.1016/j.jaci.2016.04.019

Cite this

van den Elzen, M. T., van Os-Medendorp, H., Röckmann-Helmbach, H., van Hoffen, E., Lebens, A. F. M., van Doorn, H., Klemans, R. J. B., Bruijnzeel-Koomen, C. A. F. M., Hack, C. E., Kaufman, L., Relan, A., & Knulst, A. C. (2016). Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk. Journal of Allergy and Clinical Immunology, 138(2), 476-481.e1. https://doi.org/10.1016/j.jaci.2016.04.019

@article{f1d0fe16ac4b4b8fb41e6746466182df,

title = "Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk",

abstract = "Background Recombinant human C1 inhibitor (rhC1INH) for on-demand treatment of hereditary angioedema is purified from milk of transgenic rabbits. It contains low amounts (",

keywords = "allergenicity, cow's milk allergy, Hereditary angioedema, intracutaneous test, intradermal testing, rabbit allergy, recombinant human C1 esterase inhibitor, skin prick test, subcutaneous administration, subcutaneous challenge",

author = "{van den Elzen}, {Mignon T.} and {van Os-Medendorp}, Harmieke and Heike R{\"o}ckmann-Helmbach and {van Hoffen}, Els and Lebens, {Ans F M} and {van Doorn}, Helma and Klemans, {Rob J B} and Bruijnzeel-Koomen, {Carla A F M} and Hack, {C. Erik} and Leonard Kaufman and Anurag Relan and Knulst, {Andr{\'e} C.}",

year = "2016",

month = aug,

day = "1",

doi = "10.1016/j.jaci.2016.04.019",

language = "English",

volume = "138",

pages = "476--481.e1",

journal = "Journal of Allergy and Clinical Immunology",

issn = "0091-6749",

publisher = "Mosby Inc.",

number = "2",

}

van den Elzen, MT, van Os-Medendorp, H, Röckmann-Helmbach, H, van Hoffen, E, Lebens, AFM, van Doorn, H, Klemans, RJB, Bruijnzeel-Koomen, CAFM, Hack, CE, Kaufman, L, Relan, A & Knulst, AC 2016, 'Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk', Journal of Allergy and Clinical Immunology, vol. 138, no. 2, pp. 476-481.e1. https://doi.org/10.1016/j.jaci.2016.04.019

Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk. / van den Elzen, Mignon T.; van Os-Medendorp, Harmieke; Röckmann-Helmbach, Heike et al.
In: Journal of Allergy and Clinical Immunology, Vol. 138, No. 2, 01.08.2016, p. 476-481.e1.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk

AU - van den Elzen, Mignon T.

AU - van Os-Medendorp, Harmieke

AU - Röckmann-Helmbach, Heike

AU - van Hoffen, Els

AU - Lebens, Ans F M

AU - van Doorn, Helma

AU - Klemans, Rob J B

AU - Bruijnzeel-Koomen, Carla A F M

AU - Hack, C. Erik

AU - Kaufman, Leonard

AU - Relan, Anurag

AU - Knulst, André C.

PY - 2016/8/1

Y1 - 2016/8/1

N2 - Background Recombinant human C1 inhibitor (rhC1INH) for on-demand treatment of hereditary angioedema is purified from milk of transgenic rabbits. It contains low amounts (

AB - Background Recombinant human C1 inhibitor (rhC1INH) for on-demand treatment of hereditary angioedema is purified from milk of transgenic rabbits. It contains low amounts (

KW - allergenicity

KW - cow's milk allergy

KW - Hereditary angioedema

KW - intracutaneous test

KW - intradermal testing

KW - rabbit allergy

KW - recombinant human C1 esterase inhibitor

KW - skin prick test

KW - subcutaneous administration

KW - subcutaneous challenge

UR - http://www.scopus.com/inward/record.url?scp=84990828662&partnerID=8YFLogxK

U2 - 10.1016/j.jaci.2016.04.019

DO - 10.1016/j.jaci.2016.04.019

M3 - Article

C2 - 27321437

AN - SCOPUS:84990828662

SN - 0091-6749

VL - 138

SP - 476-481.e1

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

IS - 2

ER -

Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this