Allergen immunotherapy for IgE-mediated food allergy: protocol for a systematic review

  • Sangeeta Dhami
  • , Ulugbek Nurmatov
  • , Giovanni Battista Pajno
  • , Montserrat Fernandez-Rivas
  • , Antonella Muraro
  • , Graham Roberts
  • , Cezmi Akdis
  • , Montserrat Alvaro-Lozano
  • , Kirsten Beyer
  • , Carsten Bindslev-Jensen
  • , Wesley Burks
  • , George du Toit
  • , Motohiro Ebisawa
  • , Philippe Eigenmann
  • , Edward Knol
  • , Mika Makela
  • , Kari Christine Nadeau
  • , Liam O'Mahony
  • , Nikolaos Papadopoulos
  • , Lars Poulsen
  • Cansin Sackesen, Hugh Sampson, Alexandra Santos, Ronald van Ree, Frans Timmermans, Aziz Sheikh

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

BACKGROUND: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated food allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in IgE-mediated food allergy.

METHODS: We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised.

DISCUSSION: The findings from this review will be used to inform the development of recommendations for EAACI's Guidelines on AIT.

Original languageEnglish
Article number6:24
JournalClinical and Translational Allergy
Volume6
DOIs
Publication statusPublished - 2016

Keywords

  • Allergy
  • Allergen immunotherapy
  • Food allergy
  • Therapy
  • Sensitisation

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