Abstract
Objective. To determine whether children with juvenile idiopathic arthritis (JIA) have lower physical fitness compared to healthy children, and to determine the clinical relevance of this impairment.
Methods. A systematic literature search was performed using MEDLINE, CINAHL, EMBASE and SPORTDiscus. The appropriate titles were identified and the data were extracted from these publications. The maximal oxygen consumption (VO2peak; in ml.kg(-1).min(-1)) during a maximal exercise test until volitional exhaustion was used as the main outcome for this review.
Results. Nine studies were identified in the literature. Data from 5 studies (144 patients) were pooled in a metaanalysis. The VO2peak of the patients with JIA was 21.8% (95% Cl 13.7, 29.9) lower than that of healthy children (p <0.0001).
Conclusion. The results of the metaanalysis suggest that children with JIA have moderate to heavy impairment in physical fitness as represented by maximal oxygen consumption compared to healthy children.
| Original language | English |
|---|---|
| Pages (from-to) | 2643-2647 |
| Number of pages | 5 |
| Journal | Journal of Rheumatology |
| Volume | 29 |
| Issue number | 12 |
| Publication status | Published - Dec 2002 |
Keywords
- exercise capacity
- metaanalysis
- exercise tolerance
- juvenile idiopathic arthritis
- RHEUMATOID-ARTHRITIS
- PHYSICAL-FITNESS