Advanced cardiac MRI techniques for evaluation of left-sided valvular heart disease

Carmen P S Blanken; Emile S Farag; S Matthijs Boekholdt; Tim Leiner; Jolanda Kluin; Aart J Nederveen; Pim van Ooij; R Nils Planken

doi:10.1002/jmri.26204

Advanced cardiac MRI techniques for evaluation of left-sided valvular heart disease

Carmen P S Blanken, Emile S Farag, S Matthijs Boekholdt, Tim Leiner, Jolanda Kluin, Aart J Nederveen, Pim van Ooij, R Nils Planken

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Abstract

The most common types of left-sided valvular heart disease (VHD) in the Western world are aortic valve stenosis, aortic valve regurgitation, and mitral valve regurgitation. Comprehensive clinical evaluation entails both hemodynamic analysis and structural as well as functional characterization of the left ventricle. Cardiac magnetic resonance imaging (MRI) is an established diagnostic modality for assessment of left-sided VHD and is progressively gaining ground in modern-day clinical practice. Detailed flow visualization and quantification of flow-related biomarkers in VHD can be obtained using 4D flow MRI, an imaging technique capable of measuring blood flow in three orthogonal directions over time. In addition, recent MRI sequences enable myocardial tissue characterization and strain analysis. In this review we discuss the emerging potential of state-of-the-art MRI including 4D flow MRI, tissue mapping, and strain quantification for the diagnosis and prognosis of left-sided VHD.

LEVEL OF EVIDENCE: 1 Technical Efficacy Stage: 1 J. Magn. Reson. Imaging 2018. J. MAGN. RESON. IMAGING 2018;48:318-329.

Original language	English
Pages (from-to)	318-329
Number of pages	12
Journal	Journal of Magnetic Resonance Imaging
Volume	48
Issue number	2
DOIs	https://doi.org/10.1002/jmri.26204
Publication status	Published - Aug 2018

Keywords

4D flow MRI
hemodynamic imaging
phase-contrast MRI
strain analysis
tissue mapping
valvular heart disease
Mitral Valve Insufficiency/diagnostic imaging
Shear Strength
Echocardiography
Prognosis
Imaging, Three-Dimensional/methods
Humans
Stress, Mechanical
Magnetic Resonance Imaging/methods
Aortic Valve Stenosis/diagnostic imaging
Heart Valve Diseases/diagnostic imaging
Heart Valves/diagnostic imaging
Heart/diagnostic imaging
Biomarkers
Heart Ventricles/diagnostic imaging
Hemodynamics
Kinetics
Aortic Valve Insufficiency/diagnostic imaging

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title = "Advanced cardiac MRI techniques for evaluation of left-sided valvular heart disease",

abstract = "The most common types of left-sided valvular heart disease (VHD) in the Western world are aortic valve stenosis, aortic valve regurgitation, and mitral valve regurgitation. Comprehensive clinical evaluation entails both hemodynamic analysis and structural as well as functional characterization of the left ventricle. Cardiac magnetic resonance imaging (MRI) is an established diagnostic modality for assessment of left-sided VHD and is progressively gaining ground in modern-day clinical practice. Detailed flow visualization and quantification of flow-related biomarkers in VHD can be obtained using 4D flow MRI, an imaging technique capable of measuring blood flow in three orthogonal directions over time. In addition, recent MRI sequences enable myocardial tissue characterization and strain analysis. In this review we discuss the emerging potential of state-of-the-art MRI including 4D flow MRI, tissue mapping, and strain quantification for the diagnosis and prognosis of left-sided VHD.LEVEL OF EVIDENCE: 1 Technical Efficacy Stage: 1 J. Magn. Reson. Imaging 2018. J. MAGN. RESON. IMAGING 2018;48:318-329.",

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author = "Blanken, {Carmen P S} and Farag, {Emile S} and Boekholdt, {S Matthijs} and Tim Leiner and Jolanda Kluin and Nederveen, {Aart J} and {van Ooij}, Pim and Planken, {R Nils}",

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year = "2018",

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AB - The most common types of left-sided valvular heart disease (VHD) in the Western world are aortic valve stenosis, aortic valve regurgitation, and mitral valve regurgitation. Comprehensive clinical evaluation entails both hemodynamic analysis and structural as well as functional characterization of the left ventricle. Cardiac magnetic resonance imaging (MRI) is an established diagnostic modality for assessment of left-sided VHD and is progressively gaining ground in modern-day clinical practice. Detailed flow visualization and quantification of flow-related biomarkers in VHD can be obtained using 4D flow MRI, an imaging technique capable of measuring blood flow in three orthogonal directions over time. In addition, recent MRI sequences enable myocardial tissue characterization and strain analysis. In this review we discuss the emerging potential of state-of-the-art MRI including 4D flow MRI, tissue mapping, and strain quantification for the diagnosis and prognosis of left-sided VHD.LEVEL OF EVIDENCE: 1 Technical Efficacy Stage: 1 J. Magn. Reson. Imaging 2018. J. MAGN. RESON. IMAGING 2018;48:318-329.

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Advanced cardiac MRI techniques for evaluation of left-sided valvular heart disease

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