TY - JOUR
T1 - Adherence to TRIPOD+AI guideline
T2 - An updated reporting assessment tool
AU - de Kanter, Emilie
AU - Kaul, Tabea
AU - Heus, Pauline
AU - de Groot, Tom M
AU - Kuijten, René Harmen
AU - Reitsma, Johannes B
AU - Collins, Gary S
AU - Hooft, Lotty
AU - Moons, Karel G M
AU - Damen, Johanna A A
N1 - Publisher Copyright:
© 2026 The Authors.
PY - 2025/12/23
Y1 - 2025/12/23
N2 - Objectives Incomplete reporting of research limits its usefulness and contributes to research waste. Numerous reporting guidelines have been developed to support complete and accurate reporting of health-care research studies. Completeness of reporting can be measured by evaluating the adherence to reporting guidelines. However, assessing adherence to a reporting guideline often lacks uniformity. In 2019, we developed a reporting adherence tool for the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) statement. With recent advances in regression and artificial intelligence (AI)/machine learning (ML)–based methods, TRIPOD + AI ( www.tripod-statment.org ) was developed to replace the TRIPOD statement. The aim of this study was to develop an updated adherence tool for TRIPOD + AI. Study Design and Setting Based on the TRIPOD + AI full reporting guideline, including the accompanying explanation and elaboration light, and TRIPOD + AI for abstracts, we updated and expanded the original TRIPOD adherence tool and refined the adherence elements and their scoring rules through discussions within the author team and a pilot test. Results The updated tool comprises of 37 main items and 136 adherence elements and includes several automated scoring rules. We developed separate TRIPOD + AI adherence tools for model development, model evaluation, and for studies describing both in a single paper. Conclusion A uniform approach to assessing reporting adherence of TRIPOD + AI allows for comparisons across various fields, monitor reporting over time, and incentivizes primary study authors to comply. Plain Language Summary Accurate and complete reporting is crucial in biomedical research to ensure findings can be effectively used. To support researchers in reporting their findings well, reporting guidelines have been developed for different study types. One such guideline is TRIPOD, which focuses on research studies about medical prediction tools. In 2024, TRIPOD was updated to TRIPOD + AI to address the increasing use of AI and ML in prediction model studies. In 2019, we developed a scoring system to evaluate how well research papers on prediction tools adhered to the TRIPOD guideline, resulting in a reporting completeness score. This score allows for easier comparison of reporting completeness across various medical fields, and to monitor improvement in reporting over time. With the introduction of TRIPOD + AI, an update of the scoring system was required to align with the new reporting recommendations. We achieved this by reviewing our previous scoring system and incorporating the new items from TRIPOD + AI to better suit studies involving AI. We believe that this system will facilitate comparisons of prediction model reporting completeness across different fields and encourage improved reporting practices.
AB - Objectives Incomplete reporting of research limits its usefulness and contributes to research waste. Numerous reporting guidelines have been developed to support complete and accurate reporting of health-care research studies. Completeness of reporting can be measured by evaluating the adherence to reporting guidelines. However, assessing adherence to a reporting guideline often lacks uniformity. In 2019, we developed a reporting adherence tool for the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) statement. With recent advances in regression and artificial intelligence (AI)/machine learning (ML)–based methods, TRIPOD + AI ( www.tripod-statment.org ) was developed to replace the TRIPOD statement. The aim of this study was to develop an updated adherence tool for TRIPOD + AI. Study Design and Setting Based on the TRIPOD + AI full reporting guideline, including the accompanying explanation and elaboration light, and TRIPOD + AI for abstracts, we updated and expanded the original TRIPOD adherence tool and refined the adherence elements and their scoring rules through discussions within the author team and a pilot test. Results The updated tool comprises of 37 main items and 136 adherence elements and includes several automated scoring rules. We developed separate TRIPOD + AI adherence tools for model development, model evaluation, and for studies describing both in a single paper. Conclusion A uniform approach to assessing reporting adherence of TRIPOD + AI allows for comparisons across various fields, monitor reporting over time, and incentivizes primary study authors to comply. Plain Language Summary Accurate and complete reporting is crucial in biomedical research to ensure findings can be effectively used. To support researchers in reporting their findings well, reporting guidelines have been developed for different study types. One such guideline is TRIPOD, which focuses on research studies about medical prediction tools. In 2024, TRIPOD was updated to TRIPOD + AI to address the increasing use of AI and ML in prediction model studies. In 2019, we developed a scoring system to evaluate how well research papers on prediction tools adhered to the TRIPOD guideline, resulting in a reporting completeness score. This score allows for easier comparison of reporting completeness across various medical fields, and to monitor improvement in reporting over time. With the introduction of TRIPOD + AI, an update of the scoring system was required to align with the new reporting recommendations. We achieved this by reviewing our previous scoring system and incorporating the new items from TRIPOD + AI to better suit studies involving AI. We believe that this system will facilitate comparisons of prediction model reporting completeness across different fields and encourage improved reporting practices.
KW - Adherence
KW - Artificial intelligence
KW - Machine learning
KW - Prediction models
KW - Reporting completeness
KW - Reporting guidelines
KW - TRIPOD
KW - TRIPOD + AI
UR - https://www.scopus.com/pages/publications/105027917139
U2 - 10.1016/j.jclinepi.2025.112118
DO - 10.1016/j.jclinepi.2025.112118
M3 - Article
C2 - 41448505
SN - 0895-4356
VL - 191
JO - Journal of Clinical Epidemiology
JF - Journal of Clinical Epidemiology
M1 - 112118
ER -